• Kumbhar, Popat
• Gurav, Shailendra
• Bhagwat, Durgacharan
• Nadaf, Sameer

Abstract

<jats:p>Increased respiratory tract infections have placed a socioeconomic load on the global healthcare system, particularly in developing nations. The lack of alternative therapeutic options has seriously threatened the health of many populations. With the use of passive, active, or physicochemical targeting techniques, nanomedicine-based delivery systems have been developed to enhance the biopharmacokinetic properties and therapeutic results of drugs effective against lung infections. Owing to their physicochemical properties, controlled in vivo behaviour, and the ability for multimodal imaging, NPs are the preferred contrast agents. This chapter provides an overview of respiratory infections and illuminates several barriers of bacterial infections. The features and benefits of nanosized materials for diagnosing various lung diseases are analysed. The current trends of different nanosystems such as lipid-based vesicles, including solid lipid NPs, nanostructured lipid carriers, polymeric micelles, dendrimers, etc., for treating several life-threatening lung infections, including COVID-19, are reviewed and discussed, highlighting their benefits and limitations. The current state of nanovaccines for treating lung infections is highlighted in a separate section. The challenges and prospects of nanostrategies for treating lung infections are considered in the last section.</jats:p>

Topics

• impedance spectroscopy
• dendrimer