| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Mann, Stephen
University of Bristol
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (25/25 displayed)
- 2020Mixed liposomes containing gram-positive bacteria lipidscitations
- 2017Self-Assembly of Colloidal Nanocomposite Hydrogels Using 1D Cellulose Nanocrystals and 2D Exfoliated Organoclay Layerscitations
- 2015Multimodal Plasmonics in Fused Colloidal Networkscitations
- 2014In situ X-ray reflectivity studies of molecular and molecular-cluster intercalation within purple membrane filmscitations
- 2014In situ X-ray reflectivity studies of molecular and molecular-cluster intercalation within purple membrane filmscitations
- 2014Molecular dynamics simulations reveal a dielectric-responsive coronal structure in protein-polymer surfactant hybrid nanoconstructscitations
- 2013Electrochemical crystallization of spatially organized copper microwire arrays within biomineralized (dentine) templatescitations
- 2013Apoferritin-encapsulated PbS quantum dots significantly inhibit growth of colorectal carcinoma cellscitations
- 2013Apoferritin-encapsulated PbS quantum dots significantly inhibit growth of colorectal carcinoma cellscitations
- 2013Directing Chondrogenesis of Stem Cells with Specific Blends of Cellulose and Silkcitations
- 2013The reinforcement effects of graphene oxide nanoplatelets on the mechanical and viscoelastic properties of natural rubber
- 2012High magnetic field quantum transport in Au nanoparticle-cellulose filmscitations
- 2012Polymer/nucleotide droplets as bio-inspired functional micro-compartmentscitations
- 2012The differential effect of apoferritin-PbS nanocomposites on cell cycle progression in normal and cancerous cellscitations
- 2011Lamellar nanocomposite films of purple membrane and poly(acrylate)
- 2011Guest-Molecule-Directed Assembly of Mesostructured Nanocomposite Polymer/Organoclay Hydrogelscitations
- 2011Supramolecular hydrogels derived from silver ion-mediated self-assembly of 5 '-guanosine monophosphatecitations
- 2010Assembly of poly(methacrylate)/purple membrane lamellar nanocomposite films by intercalation and in situ polymerisationcitations
- 2009Structure and Properties of Silicified Purple Membrane Thin Filmscitations
- 2009Hydroxyapatite pattern formation in PVA gelscitations
- 2009Membrane stabilization and transformation in organoclay-vesicle hybrid constructscitations
- 2009Immobilisation and encapsulation of functional protein-inorganic constructscitations
- 2007Bio-functional mesolamellar nanocomposites based on inorganic/polymer intercalation in purple membrane (bacteriorhodopsin) filmscitations
- 2007Biomimetic hydroxyapatite-drug nanocrystals as potential bone substitutes with antitumor drug delivery propertiescitations
- 2007Influence of polymer co-intercalation on guest release from aminopropyl-functionalized magnesium phyllosilicate mesolamellar nanocompositescitations
Places of action
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article
Immobilisation and encapsulation of functional protein-inorganic constructs
Abstract
Self-assembly methods for the immobilisation or encapsulation of the positively charged redox protein, cytochrome c (cyt c), in layered organoclays or silica nanoparticles, respectively, are described and contrasted. Protein-polymer-organoclay nanocomposites are produced by spontaneous restacking of delaminated aminopropyl-functionalised magnesium phyllosilicate sheets in the presence of an aqueous solution of poly( sodium 4-styrene sulfonate) (PSS) and cyt c. In contrast, single molecules of cyt c are encapsulated in silica nanoparticles by sol-gel reactions at the oil-water interface of microemulsion water droplets. In both cases, the protein molecules remain structurally intact after entrapment, are accessible to small molecule redox agents, exhibit excellent peroxidase activity in the presence of hydrogen peroxide, and show enhanced stability and catalytic properties under adverse conditions of pH. The ability to prepare functional protein - inorganic conjugates in general could significantly extend the technological scope of biological products and processes, and should therefore be an important adjunct in the translation of synthetic biology to real-life applications.