| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Patil, Avinash J.
University of Bristol
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2017Self-Assembly of Colloidal Nanocomposite Hydrogels Using 1D Cellulose Nanocrystals and 2D Exfoliated Organoclay Layerscitations
- 2016Chitin and carbon nanotube composites as biocompatible scaffolds for neuron growthcitations
- 2013Ionic liquids-based processing of electrically conducting chitin nanocomposite scaffolds for stem cell growthcitations
- 2013Directing Chondrogenesis of Stem Cells with Specific Blends of Cellulose and Silkcitations
- 2013The reinforcement effects of graphene oxide nanoplatelets on the mechanical and viscoelastic properties of natural rubber
- 2012Polymer/nucleotide droplets as bio-inspired functional micro-compartmentscitations
- 2011Guest-Molecule-Directed Assembly of Mesostructured Nanocomposite Polymer/Organoclay Hydrogelscitations
- 2011Supramolecular hydrogels derived from silver ion-mediated self-assembly of 5 '-guanosine monophosphatecitations
- 2009Membrane stabilization and transformation in organoclay-vesicle hybrid constructscitations
- 2009Immobilisation and encapsulation of functional protein-inorganic constructscitations
- 2007Bio-functional mesolamellar nanocomposites based on inorganic/polymer intercalation in purple membrane (bacteriorhodopsin) filmscitations
- 2007Influence of polymer co-intercalation on guest release from aminopropyl-functionalized magnesium phyllosilicate mesolamellar nanocompositescitations
Places of action
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article
Influence of polymer co-intercalation on guest release from aminopropyl-functionalized magnesium phyllosilicate mesolamellar nanocomposites
Abstract
Protonation of the interlayer aminopropyl groups of a synthesized organo- functionalized 2 : 1 trioctahedral magnesium phyllosilicate was used to prepare exfoliated cationic organoclay dispersions that were subsequently re- assembled in the presence of anionic guest molecules, such as ibuprofen, epigallocatechin gallate ( EGCG), poly( styrene sulfonate) ( PSS), poly( acrylic acid) ( PAA), or polymethyl- acrylamidopropanesulfonic acid ( PMAPSA), to produce a range of novel intercalated layered nanocomposites. Re- assembled organoclays containing ibuprofen or epigallocatechin gallate co- intercalated with various types of polymer molecules were also prepared. In each case, X- ray diffraction studies confirmed the formation of intercalated or co- intercalated lamellar nanocomposites with expanded interlayer ( d(001)) spacings. We demonstrate that pH dependent oxidation of EGCG is curtailed when intercalated within the organoclay interlayers. Significantly, the ibuprofen release profiles in water or simulated gastric fluid ( pH = 2) indicated that extraction of the biomolecule into solution could be delayed or accelerated depending on the type of polymer co- intercalated. Whereas co- intercalation of PSS increased the rate of ibuprofen release, extraction of the drug from nanocomposites containing PMAPSA was significantly reduced. In contrast, PAA- containing ibuprofen/ organoclay nanocomposites showed release profiles that were only marginally reduced compared with those for ibuprofen alone. Steric and electrostatic interactions between the entrapped polymer and drug molecules are discussed to account for these observations.