• Mackinnon, Marina J.
• Picchio, Camila A.
• Lazarus, Jeffrey V.
• Forns, Xavier
• Lens, Sabela
• Buti, Maria
• Rando-Segura, Ariadna
• Araujo, Silvia G.
• Rodríguez-Frías, Francisco
• Nomah, Daniel K.
• Selm, Lena Van
• Nuñez, Carmen López
• Portero, Javier Pamplona
• Martró, Elisa
• Fernández, Emma
• Tajes, Sergio Rodriguez

Abstract

<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Chronic infection with HBV is responsible for &gt;50% of all hepatocellular cancer cases globally and disproportionately affects sub-Saharan African (sSA) countries. Migration from these countries to Europe has increased substantially in recent years, posing unique challenges to health systems. The aim of this study was to carry out a community-based intervention to increase HBV screening, vaccination, and linkage to care among sSA migrants in Catalonia, Spain.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>This was a prospective cohort study. Participants ≥18 years were offered community-based HBV screening between 20/11/20 and 21/01/22. Rapid HBV testing and blood sample collection utilizing plasma separation cards were carried out and linkage to care was offered to all participants. HBV vaccination and post-test counseling were performed at a second visit in the community. The main outcome was the odds of those with current HBV infection being successfully linked to hepatology. Rates of completing the care cascade of this model were analyzed.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>In the present study, 444 people undergo screening, with 50.6% of participants showing evidence of past or current HBV infection, including an HBsAg prevalence of 9.2%. Migrants with current HBV infection exhibit 5.2 times higher odds of successful linkage to care compared to those in need of post-test counseling or vaccination. The study achieves a successful linkage to care rate of 72% for all participants, with specialist appointments arranged within 15.5 days.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>This community-based HBV screening program provides evidence of a successful model for identifying and providing care, including vaccination, to west African migrants at high risk of HBV infection who may otherwise not engage in care.</jats:p></jats:sec>

Topics

• impedance spectroscopy
• size-exclusion chromatography