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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Monteiro, Sérgio Neves
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Publications (4/4 displayed)
- 2023Additive manufacturing of poly (lactic acid)/hydroxyapatite/carbon nanotubes biocomposites for fibroblast cell proliferationcitations
- 2022Comparison between Synthetic and Biodegradable Polymer Matrices on the Development of Quartzite Waste-Based Artificial Stonecitations
- 2021Clay Ceramic Waste as Pozzolan Constituent in Cement for Structural Concretecitations
- 2012Zirconia Blocks Properties Used for CAD/CAM Dentistry Restorationscitations
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article
Additive manufacturing of poly (lactic acid)/hydroxyapatite/carbon nanotubes biocomposites for fibroblast cell proliferation
Abstract
<jats:title>Abstract</jats:title><jats:p>Bone tissue is one of the most important in the human body. In this study, <jats:italic>scaffolds</jats:italic> of poly (lactic acid) PLA reinforced with hydroxyapatite (HA) and carbon nanotubes (CNT) were manufactured, evaluating their mechanical and biological properties. HA was synthesized by wet method and characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The <jats:italic>scaffolds</jats:italic> were produced using additive manufacturing and characterized by optical microscopy, SEM, thermogravimetric analysis (TGA), Raman spectroscopy and biological tests. The SEM results showed that the PLA surface was affected by the incorporation of CNT. TG showed that the incorporation of HA into the polymer matrix compromised the thermal stability of PLA. On the other hand, the incorporation of CNT to the polymer and the impregnation with HA on the surface by thermal effect increased the stability of PLA/CNT <jats:italic>scaffolds</jats:italic>. Raman spectra indicated that HA impregnation on the surface did not modify the polymer or the ceramic. In the compression tests, PLA and PLA/CNT <jats:italic>scaffolds</jats:italic> displayed the best compressive strength. In the biological tests, more than 85% of the cells remained viable after 48 h of incubation with all tested <jats:italic>scaffolds</jats:italic> and groups with CNT in the composition disclosing the best results.</jats:p>