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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Hussain, Nadia
in Cooperation with on an Cooperation-Score of 37%
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Publications (3/3 displayed)
- 2023Fabrication of novel oxochalcogens halides of manganese and tin nanocomposites as highly efficient photocatalysts for dye degradation and excellent antimicrobial activitycitations
- 2023Construction of Te-ZnO@S-g-C3N4 Heterojunction Nanocomposites for the Efficient Removal of Methylene Blue, Antifungal Activity, and Adsorption of Cr(VI) Ioncitations
- 2023High throughput biochemical profiling, and functional potential analysis for valorization of grape pedunclescitations
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article
High throughput biochemical profiling, and functional potential analysis for valorization of grape peduncles
Abstract
<jats:title>Abstract</jats:title><jats:p><jats:italic>Vitis vinifera</jats:italic> L., commonly known as grape is a major fruit crop in the world. Grapes seem to confer health benefits due to their chemical components, biological and antioxidant activities. The present study is conducted to evaluate the biochemical constituents, antioxidant, and antimicrobial potential of ethanolic grape peduncles (EGP) extract. The result of phytochemical analysis revealed the presence of various phytochemicals such as flavonoid, tannin, carbohydrates, alkaloids, cardiac glycoside, phenol, steroid, terpenoids, quinones and anthraquinones. Furthermore, total phenolic content (TPC) and total flavonoid contents (TFC) were 7.35 ± 0.25 mg GAE/g (Gallic Acid Equivalent per gram) and 29.67 ± 0.13 mg QE/g (Quercetin Equivalent per gram) respectively. DPPH (2, 2-diphenyl-1-picrylhydrazyl) free radical scavenging assay revealed IC<jats:sub>50</jats:sub> = 159.3 μg/mL. The antibacterial and antifungal study disclosed that the extract was highly potent against <jats:italic>Salmonella typhi</jats:italic> with maximum zone of inhibition of 27.2 ± 1.60 mm and <jats:italic>Epidermophyton floccosum</jats:italic> with 74 ± 1.81% inhibition. The extract was analyzed for its cytotoxicity and antileishmanial activity and showed no activity against HeLa cell line and promastigotes of <jats:italic>Leishmania major</jats:italic>. Elements Fe, Mn, Ni, Pb and Cd were determined by atomic absorption spectroscopy and approximately 50 compounds were identified by Gas Chromatography-Mass Spectrometry (GC–MS). Current work suggest that grape peduncles can be a promising source of bioactive medicinal component.</jats:p>