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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Habibovic, Pamela
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (31/31 displayed)
- 2024Extracellular matrix mimetic supramolecular hydrogels reinforced with covalent crosslinked mesoporous silica nanoparticles
- 2024Optimization of a tunable process for rapid production of calcium phosphate microparticles using a droplet-based microfluidic platformcitations
- 2023Polymer film-based microwell array platform for long-term culture and research of human bronchial organoidscitations
- 2023Decoupling the role of chemistry and microstructure in hMSCs response to an osteoinductive calcium phosphate ceramiccitations
- 2023Matrix metalloproteinase degradable, in situ photocrosslinked nanocomposite bioinks for bioprinting applicationscitations
- 2022Sustained local ionic homeostatic imbalance caused by calcification modulates inflammation to trigger heterotopic ossificationcitations
- 2022Assessment of Cell-Material Interactions in Three Dimensions through Dispersed Coaggregation of Microsized Biomaterials into Tissue Spheroidscitations
- 2021Biomimetic Mechanically Strong One-Dimensional Hydroxyapatite/Poly(d,l-lactide) Composite Inducing Formation of Anisotropic Collagen Matrixcitations
- 2021Cobalt-containing calcium phosphate induces resorption of biomineralized collagen by human osteoclastscitations
- 2021Biodegradable Elastic Sponge from Nanofibrous Biphasic Calcium Phosphate Ceramic as an Advanced Material for Regenerative Medicinecitations
- 20213D porous Ti6Al4V-beta-tricalcium phosphate scaffolds directly fabricated by additive manufacturingcitations
- 2021Injectable, self-healing mesoporous silica nanocomposite hydrogels with improved mechanical propertiescitations
- 2020Intestinal Organoid Culture in Polymer Film-Based Microwell Arrayscitations
- 2017Development of a microfluidic platform integrating high-resolution microstructured biomaterials to study cell-material interactionscitations
- 2017Deconvoluting the Bioactivity of Calcium Phosphate-Based Bone Graft Substitutescitations
- 2017Deconvoluting the Bioactivity of Calcium Phosphate-Based Bone Graft Substitutes:Strategies to Understand the Role of Individual Material Propertiescitations
- 2017Enhancing regenerative approaches with nanoparticlescitations
- 2016The Effects of Crystal Phase and Particle Morphology of Calcium Phosphates on Proliferation and Differentiation of Human Mesenchymal Stromal Cellscitations
- 2016Independent effects of the chemical and microstructural surface properties of polymer/ceramic composites on proliferation and osteogenic differentiation of human MSCscitations
- 2016Independent effects of the chemical and microstructural surface properties of polymer/ceramic composites on proliferation and osteogenic differentiation of human MSCscitations
- 2015Elucidating the individual effects of calcium and phosphate ions on hMSCs by using composite materialscitations
- 2010Biomimetic calcium phosphate coatings on recombinant spider silk fibrescitations
- 2009Effects of soluble cobalt and cobalt incorporated into calcium phosphate layers on osteoclast differentiation and activationcitations
- 2009Angiogenesis in Calcium Phosphate Scaffolds by Inorganic Copper Ion Releasecitations
- 2008Osteoconduction and osteoinduction of low-temperature 3D printed bioceramic implantscitations
- 2008Comparative in vivo study of six hydroxyapatite-based bone graft substitutescitations
- 2007Biological performance in goats of a porous titanium alloy-biphasic calcium phosphate compositecitations
- 2006Influence of physico-chemical properties, macro- and microstructure on osteoinductive potential of calcium-phosphate ceramicscitations
- 2006Relevance of osteoinductive biomaterials in critical-sized orthotopic defectcitations
- 20053D microenvironment as essential element for osteoinduction by biomaterialscitations
- 2004Influence of octacalcium phosphate coating on osteoinductive properties of biomaterialscitations
Places of action
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article
Influence of octacalcium phosphate coating on osteoinductive properties of biomaterials
Abstract
<p>In this study, we investigated the influence of octacalcium phosphate (OCP) coating on osteoinductive behaviour of the biomaterials.</p><p>Porous titanium alloy (Ti6Al4V), hydroxyapatite (HA), biphasic calcium phosphate (BCP) and polyethylene glyco terephtalate/polybuthylene terephtalate (PEGT-PBT) copolymer, all uncoated and coated with biomimetically produced OCP, were implanted in back muscles of 10 goats for 6 and 12 weeks. Uncoated Ti6Al4V and HA did not show any bone formation after intramuscular implantation. All OCP coated implants, except PEGT-PBT did induce bone in the soft tissue. The reason for the non-inductive behaviour of the copolymer is probably its softness, that makes it impossible to maintain its porous shape after implantation. Both uncoated and OCP coated BCP induced bone. However, the amount of animals in which the bone was induced was higher in the coated BCP implants in comparison to the uncoated ones.</p><p>Osteoinductive potential of biomaterials is influenced by various material characteristics, such as chemical composition, crystallinity, macro- and microstructure.</p><p>OCP coating has a positive effect on osteoinductivity of the biomaterials. The combination of the advantages of biomimetic coating method above traditional methods, and a good osteoinductivity of OCP coating that is produced by using this method, opens new possibilities for designing more advanced orthopaedic implants. (C) 2004 Kluwer Academic Publishers.</p>