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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Lee, Koon-Yang
Imperial College London
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2023Predicting filling efficiency of composite resin injection repaircitations
- 2021<i>Komagataeibacter</i> Tool Kit (KTK): A Modular Cloning System for Multigene Constructs and Programmed Protein Secretion from Cellulose Producing Bacteria.citations
- 2020Nanomaterials Derived from Fungal Sources-Is It the New Hype?citations
- 2020Upcycling Poultry Feathers with (Nano)cellulose:Sustainable Composites Derived from Nonwoven Whole Feather Preformscitations
- 2020High porosity cellulose nanopapers as reinforcement in multi-layer epoxy laminatescitations
- 2019Nanocellulose reinforced polymer composites: Computational analysis of structure-mechanical properties relationshipscitations
- 2019Cationic starch as strengthening agent in nanofibrillated and bacterial cellulose nanopapers
- 2019Nanomaterials Derived from Fungal Sources - Is It the New Hype?citations
- 2018Better togethercitations
- 2018Thinner and better: (Ultra-)low grammage bacterial cellulose nanopaper-reinforced polylactide composite laminates
- 2017Sample geometry dependency on the measured tensile properties of cellulose nanopaperscitations
- 2016Understanding the Dispersion and Assembly of Bacterial Cellulose in Organic Solventscitations
- 2016Ductile unidirectional continuous rayon fibre-reinforced hierarchical compositescitations
- 2014Bacterial Cellulose Nanopaper as Reinforcement for Polylactide Compositescitations
- 2014Aligned unidirectional PLA/bacterial cellulose nanocomposite fibre reinforced PDLLA compositescitations
- 2014On the use of nanocellulose as reinforcement in polymer matrix compositescitations
- 2013Porous copolymers of ε-caprolactone as scaffolds for tissue engineeringcitations
- 2012Nano-fibrillated cellulose vs bacterial cellulose
- 2012Carbon Fiber: Properties, Testing, and Analysiscitations
- 2012Interfaces in Cross-Linked and Grafted Bacterial Cellulose/Poly(Lactic Acid) Resin Compositescitations
- 2012Nano-fibrillated cellulose vs bacterial cellulose:Reinforcing ability of nanocellulose obtained topdown or bottom-up
- 2009Renewable nanocomposite polymer foams synthesized from Pickering emulsion templatescitations
- 2009Surface functionalisation of bacterial cellulose as the route to produce green polylactide nanocomposites with improved propertiescitations
Places of action
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article
Porous copolymers of ε-caprolactone as scaffolds for tissue engineering
Abstract
<p>A series of random copolymers were synthesized via the copolymerization of a carbohydrate lactone, acetic acid 5-acetoxy-6-oxotetrahydropyran-2-yl methyl ester (1), and e-caprolactone. The copolymers were characterized by nuclear magnetic resonance (NMR) spectroscopy, size exclusion chromatography (SEC), differential scanning calorimetry (DSC), and thermal gravimetric analysis (TGA). Copolymers (P1-P4) were produced with typical carbohydrate ester compositions of 1-4 mol %. These copolymers are semi-crystalline and can be processed into thin films with Young's moduli of 300-420 MPa, values that exceed that for polycaprolactone (PCL). The copolymers were processed using supercritical carbon dioxide (scCO(2), 35 degrees C, 200 bar) into foamed, porous scaffolds, which were characterized by dynamic mechanical thermal analyses (DMTA), mercury porosimetry, and scanning electron microscopy (SEM). The copolymer foams showed increased pore size with increasing carbohydrate ester content. The average pore size increased from 71 mu m (PCL) to 319 mu m (P4). The foamed scaffolds have normalized storage moduli ranging from 37 MPa cm(3) g(-1) (P4) to 109 MPa cm(3) (P1). A representative copolymer foamed scaffold, tested according to ISO 10993-5 criteria, was cytocompatible for cell culture. MC3T3 cells cultured on a film of this copolymer showed increased relative metabolic activities compared to cells cultured on a PCL film. When primary bovine chondrocytes were cultured on the foamed scaffolds, increased cell penetration into the random copolymer foam was observed compared to PCL foams.</p>