• Lau, Kenneth K. S.
• Stufflet, David R.
• Nejati, Siamak
• Bose, Ranjita K.

Abstract

<p>Poly(ethylene oxide) (PEO), a biomedically important polymer, has been synthesized using a novel liquid-free initiated chemical vapor deposition (iCVD) via a ring-opening cationic polymerization mechanism. In addition, a grafting scheme was used to graft polymerize PEO onto amine-terminated surfaces. FTIR, NMR, and XPS showed a stoichiometric match to linear PEO homopolymer. In addition, XPS confirmed the graft polymerization of PEO to amine anchors on silicon with a high graft density. XPS and GPC were used to measure independently the grafted polymer molecular weight that also showed a narrow weight distribution. The grafted iCVD PEO surfaces were effective in minimizing nonspecific protein adsorption using a fluorescently labeled bovine serum albumin assay.</p>

Topics

• density
• surface
• x-ray photoelectron spectroscopy
• Silicon
• molecular weight
• homopolymer
• Nuclear Magnetic Resonance spectroscopy
• amine
• chemical vapor deposition