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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Merkoçi, Arben
Ministerio de Ciencia e Innovación
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (18/18 displayed)
- 2023One-Step Laser Nanostructuration of Reduced Graphene Oxide Films Embedding Metal Nanoparticles for Sensing Applicationscitations
- 2023Freestanding laser-induced two dimensional heterostructures for self-contained paper-based sensorscitations
- 2023Nanostructure Tuning of Gold Nanoparticles Films via Click Sinteringcitations
- 2023Nanostructure Tuning of Gold Nanoparticles Films via Click Sinteringcitations
- 2022Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care testscitations
- 2020Chitin nanofiber paper toward optical (bio)sensing applicationscitations
- 2019Paper based photoluminescent sensing platform with recognition sites for tributyltincitations
- 2018Electrochromic molecular imprinting sensor for visual and smartphone-based detectionscitations
- 2011Variable behaviour of flexible N,O-mixed pyrazole ligand towards Zn(ii), Cd(ii) and Hg(ii) ions. Synthesis, crystal structure and fluorescent propertiescitations
- 2010Immunosensing using nanoparticlescitations
- 2010Use of Sequential Injection Analysis to construct a potentiometric electronic tongue: Application to the multidetermination of heavy metalscitations
- 2010Use of Sequential Injection Analysis to construct a potentiometric electronic tongue: Application to the multidetermination of heavy metalscitations
- 2005Integration of a glucose biosensor based on an epoxy-graphite- TTF·TCNQ-GOD biocomposite into a FIA systemcitations
- 2005Magnetically trigged direct electrochemical detection of DNA hybridization using Au67 quantum dot as electrical tracercitations
- 2005Glucose biosensor based on carbon nanotube epoxy compositescitations
- 2005Sensitive stripping voltammetry of heavy metals by using a composite sensor based on a built-in bismuth precursorcitations
- 2003Rapid electrochemical genosensor assay using a streptavidin carbon-polymer biocomposite electrodecitations
- 2003Graphite-epoxy composites as a new transducing material for electrochemical genosensingcitations
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article
Magnetically trigged direct electrochemical detection of DNA hybridization using Au67 quantum dot as electrical tracer
Abstract
A novel gold nanoparticle-based protocol for detection of DNA hybridization based on a magnetically trigged direct electrochemical detection of gold quantum dot tracers is described. It relies on binding target DNA (here called DNA1) with Au67 quantum dot in a ratio 1:1, followed by a genomagnetic hybridization assay between Au67-DNA1 and complementary probe DNA (here called DNA2) marked paramagnetic beads. Differential pulse voltammetry is used for a direct voltammetric detection of resulting Au 67 quantum dot-DNA1/DNA2-paramagnetic bead conjugate on magnetic graphite-epoxy composite electrode. The characterization, optimization, and advantages of the direct electrochemical detection assay for target DNA are demonstrated. The two main highlights of presented assay are (1) the direct voltammetric detection of metal quantum dots obviates their chemical dissolution and (2) the Au67 quantum dot-DNA1/DNA2-paramagnetic bead conjugate does not create the interconnected three-dimensional network of Au-DNA duplex-paramagnetic beads as previously developed nanoparticle DNA assays, pushing down the achievable detection limits. © 2005 American Chemical Society.