| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Depero, Laura Eleonora
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (18/18 displayed)
- 2020Micro-Raman Spectroscopy Investigation of Crystalline Phases in EAF Slagcitations
- 2016Energetics of surface confined ferritin during iron loadingcitations
- 2013Insights on growth and nanoscopic investigation of uncommon iron oxide polymorphscitations
- 2013Effect of microblasting on cathodic arc evaporation CrN coatingscitations
- 2013Sensitive determination of the Young's modulus of thin films by polymeric microcantileverscitations
- 2013Sensitive determination of the Young's modulus of thin films by polymeric microcantileverscitations
- 2013All‐Oxide Raman‐Active Traps for Light and Matter: Probing Redox Homeostasis Model Reactions in Aqueous Environmentcitations
- 2013Metal fractionation in soils and assessment of environmental contamination in Vallecamonica, Italycitations
- 2013Triggering and Monitoring Plasmon‐Enhanced Reactions by Optical Nanoantennas Coupled to Photocatalytic Beads
- 2012In situ compact tensile test device for polymer nanocomposite specimens to be analyzed in an x-ray microdiffractometer
- 2011A new non-destructive method for chemical analysis of particulate matter filters: the case of manganese air pollution in Vallecamonica (Italy).citations
- 2008Effect of the mechanochemical treatment of a V2O5/MoO3 oxide mixture on its propertiescitations
- 2008The international VAMAS project on X-ray reflectivity measurements for evaluation of thin films and multilayers - Preliminary results from the second round-robincitations
- 2007Biomaterial thin film deposition and characterization by means of MAPLE techniquecitations
- 2005In situ X-ray diffraction study of tarnishing process of Ag and Ag-alloys
- 2005Bacteria enclosure between silica-coated membranes for the degradation of organic compounds in contaminated watercitations
- 2004Melting of Nanostructured Drugs Embedded into a Polymeric Matrixcitations
- 2003Nanocrystalline SnO2-Based Thin Films Obtained by Sol−Gel Route: A Morphological and Structural Investigationcitations
Places of action
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article
Melting of Nanostructured Drugs Embedded into a Polymeric Matrix
Abstract
The melting behavior of nanostructured organic materials (drugs) embedded into a cross-linked polymeric matrix was studied for the first time. The complex microstructure of these nanocomposites, yielded by the polymer matrix in which molecular clusters and nanocrystals of drug plus a cospiquous fraction of water are confined, demanded synergic application of thermal analysis and temperature resolved X-ray diffraction. A relevant depression of the melting point of the embedded drug with respect to the bulk drug was experimentally demonstrated. The coherent domain size of the embedded drug nanocrystals was independently evaluated by thermal and diffraction data and results were in agreement. This indicates that the adopted thermodynamic melting model, based on Laplace and Gibbs−Duhem equations and developed for simpler systems, can be successfully assessed for describing drug/polymer nanocomposites, and, potentially, other classes of organic nanocomposites.