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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Heinke, Lars
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (28/28 displayed)
- 2023Nanoporous Films with Oriented Arrays of Molecular Motors for Photoswitching the Guest Adsorption and Diffusioncitations
- 2020Proton-conduction photomodulation in spiropyran-functionalized MOFs with large on–off ratio
- 2020Zusammenwirken elektronischer und sterischer Effekte bei der Tieftemperatur‐CO‐Oxidation an Einzelatom‐Metallzentren in defekt‐manipuliertem HKUST‐1citations
- 2020Interplay of Electronic and Steric Effects to Yield Low‐Temperature CO Oxidation at Metal Single Sites in Defect‐Engineered HKUST‐1citations
- 2020An enantioselective e‐nose: An array of nanoporous homochiral MOF films for stereospecific sensing of chiral odors
- 2020Advanced Photoresponsive Materials Using the Metal–Organic Framework Approachcitations
- 2019Surface‐Mounted Metal–Organic Frameworks: Crystalline and Porous Molecular Assemblies for Fundamental Insights and Advanced Applicationscitations
- 2019Switching the enantioselectivity of nanoporous host materials by light
- 2018Series of Photoswitchable Azobenzene-Containing Metal–Organic Frameworks with Variable Adsorption Switching Effectcitations
- 2018Water as a modulator in the synthesis of surface-mounted metal–organic framework films of type HKUST-1citations
- 2018Smart nanoporous metal–organic frameworks by embedding photochromic molecules – state of the art and future perspectivescitations
- 2017Defects as Color Centers: The Apparent Color of Metal–Organic Frameworks Containing Cu2+-Based Paddle-Wheel Unitscitations
- 2016The options of interference microscopy to explore the significance of intracrystalline diffusion and surface permeation for overall mass transfer on nanoporous materials: The options of interference microscopy to explore the significance ofintracrystalline diffusion and surface permeation for overall masstransfer on nanoporous materials
- 2016Significance of concentration-dependent intracrystalline diffusion and surface permeation for overall mass transfer
- 2016Negative, anisotropic thermal expansion in monolithic thin films of crystalline metal-organic frameworkscitations
- 2015Photoswitching in nanoporous, crystalline solids: an experimental and theoretical study for azobenzene linkers incorporated in MOFs.citations
- 2015Free-Standing Nanomembranes Based on Selective CVD Deposition of Functional Poly- p -xylylenescitations
- 2015Free-Standing Nanomembranes Based on Selective CVD Deposition of Functional Poly- p -xylylenescitations
- 2015Transparent films of metal-organic frameworks for optical applicationscitations
- 2015Enantioselective adsorption in homochiral metal-organic frameworks: the pore size influence
- 2015Transport in nanoporous materials including MOFs : the applicability of Fick’s laws
- 2014The surface barrier phenomenon at the loading of metal-organic frameworkscitations
- 2014Photoswitching in Two-Component Surface-Mounted Metal-Organic Frameworks: Optically Triggered Release from a Molecular Containercitations
- 2014Interaction of Human Plasma Proteins with Thin Gelatin-Based Hydrogel Films: A QCM-D and ToF-SIMS Studycitations
- 2013Adsorption and diffusion in thin films of nanoporous metal-organic frameworks: ferrocene in SURMOF Cu-2(ndc)(2)(dabco)citations
- 2013Systems Chemistry at marginal Interfaces
- 2010Assessing Molecular Transport Properties of Nanoporous Materials by Interference Microscopycitations
- 2008Assessing one-dimensional diffusion in nanoporous materials from transient concentration profiles
Places of action
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article
Interaction of Human Plasma Proteins with Thin Gelatin-Based Hydrogel Films: A QCM-D and ToF-SIMS Study
Abstract
International audience ; In the fields of surgery and regenerative medicine, it is crucial to understand the interactions of proteins with the biomaterials used as implants. Protein adsorption directly influences cell-material interactions in vivo and, as a result, regulates, for example, cell adhesion on the surface of the implant. Therefore, the development of suitable analytical techniques together with well-defined model systems allowing for the detection, characterization, and quantification of protein adsorbates is essential. In this study, a protocol for the deposition of highly stable, thin gelatin-based films on various substrates has been developed. The hydrogel films were characterized morphologically and chemically. Due to the obtained low thickness of the hydrogel layer, this setup allowed for a quantitative study on the interaction of human proteins (albumin and fibrinogen) with the hydrogel by Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D). This technique enables the determination of adsorbant mass and changes in the shear modulus of the hydrogel layer upon adsorption of human proteins. Furthermore, Secondary Ion Mass Spectrometry and principal component analysis was applied to monitor the changed composition of the topmost adsorbate layer. This approach opens interesting perspectives for a sensitive screening of viscoelastic biomaterials that could be used for regenerative medicine.