| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Mezzenga, Raffaele
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2024Gold recovery from E-waste by food-waste amyloid aerogelscitations
- 2024Hybrid amyloid-chitin nanofibrils for magnetic and catalytic aerogelscitations
- 2024Synthesis of bottlebrush polymers with spontaneous self-assembly for dielectric generatorscitations
- 2021Polysaccharide-reinforced amyloid fibril hydrogels and aerogelscitations
- 2020Structure-property relationships of cellulose nanofibril hydro- and aerogels and their building blockscitations
- 2017Cofibrillization of pathogenic and functional amyloid proteins with gold nanoparticles against amyloidogenesiscitations
- 2016Magnetic assembly of transparent and conducting graphene-based functional compositescitations
- 2016Solvent-mediated conductance increase of dodecanethiol-stabilized gold nanoparticle monolayers
- 2014Stimuli-responsive magnetic properties from liquid-crystalline elastomer nanocomposites
- 2013Core-shell nanoparticle monolayers at planar liquid-liquid interfaces: effects of polymer architecture on the interface microstructurecitations
- 2013Enhanced properties of polyurea elastomeric nanocomposites with anisotropic functionalised nanofillerscitations
- 2013Nanotopographic surfaces with defined surface chemistries from amyloid fibril networks can control cell attachmentcitations
- 2010A New Supramolecular Route for Using Rod-Coil Block Copolymers in Photovoltaic Applicationscitations
- 2008Direct Imaging of Nanoscopic Plastic Deformation below Bulk Tg and Chain Stretching in Temperature-Responsive Block Copolymer Hydrogels by Cryo-TEMcitations
- 2007Phase behavior and temperature-responsive molecular filters based on self-assembly of polystyrene-block-poly(N-isopropylacrylamide)-block-polystyrenecitations
Places of action
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article
Nanotopographic surfaces with defined surface chemistries from amyloid fibril networks can control cell attachment
Abstract
We show for the first time the possibility of using networks of amyloid fibrils, adsorbed to solid supports and with plasma polymer coatings, for the fabrication of chemically homogeneous surfaces with well-defined nanoscale surface features reminiscent of the topography of the extracellular matrix. The robust nature of the fibrils allows them to withstand the plasma polymer deposition conditions used with no obvious deleterious effect, thus enabling the underlying fibril topography to be replicated at the polymer surface. This effect was seen despite the polymer coating thickness being an order of magnitude greater than the fibril network. The in vitro culture of fibroblast cells on these surfaces resulted in increased attachment and spreading compared to flat plasma polymer films with the same chemical composition. The demonstrated technique allows for the rapid and reproducible fabrication of substrates with nanoscale fibrous topography that we believe will have applications in the development of new biomaterials allowing, for example, the investigation of the effect of extracellular matrix mimicking nanoscale morphology on cellular phenotype.