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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Hinge, Mogens
Aarhus University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2021Real-time ageing of polyesters with varying diolscitations
- 2021A low-cost tabletop tensile tester with optical extensometercitations
- 2020Accelerating effect of pigments on poly(acrylonitrile butadiene styrene) degradationcitations
- 2020Facile Access to Disulfide/Thiol Containing Poly(glycidyl methacrylate) Brushes as Potential Rubber Adhesive Layerscitations
- 2020Facile Access to Disulfide/Thiol Containing Poly(glycidyl methacrylate) Brushes as Potential Rubber Adhesive Layerscitations
- 2019Accelerated physical ageing of poly(1,4-cyclohexylenedimethylene-co-2,2,4,4-tetramethyl-1,3-cyclobutanediol terephthalate)citations
- 2018Straight forward approach for obtaining relaxation-recovery data
- 2018Efficient bonding of ethylene-propylene-diene M-class rubber to stainless steel using polymer brushes as a nanoscale adhesivecitations
- 2016Temperature- and time dependency on high friction poly(styrene-co-butyl methacrylate) coated papercitations
- 2015Nonfouling Tunable beta CD Dextran Polymer Films for Protein Applicationscitations
- 2015Nonfouling tunable βCD dextran polymer films for protein applicationscitations
- 2015Calcite nucleation on the surface of PNIPAM-PAAc micelles studied by time resolved in situ PXRDcitations
- 2014Durability of PEEK adhesive to stainless steel modified with aryldiazonium saltscitations
- 2013Synthesis and photovoltaic properties from inverted geometry cells and roll-to-roll coated large area cells from dithienopyrrole-based donor–acceptor polymerscitations
- 2013Synthesis and photovoltaic properties from inverted geometry cells and roll-to-roll coated large area cells from dithienopyrrole-based donor–acceptor polymerscitations
- 2009The use of dielectric spectroscopy in the investigation of the effect of polymer choice on the flocculation of polystyrene particlescitations
Places of action
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article
Nonfouling tunable βCD dextran polymer films for protein applications
Abstract
Polymeric β-cyclodextrin (βCD) films tunable with respect to thickness and βCD content were prepared in order to develop a suitable platform, allowing for inclusion of nonpolar guest molecules in the βCD cavity, while suppressing nonspecific protein adsorption. The βCD films were synthesized from linear βCD dextran polymers, and grafted onto silicon oxide surfaces by "click" chemistry. Topographic and morphological characteristics are controllable by reaction conditions and polymer type, with average film heights from 2.5 to 12.5 nm. Reversible introduction of electrostatic charges in the βCD dextran by complex formation with 1-adamantanecarboxylic acid prior to surface grafting resulted in a thinner and denser film, presumably by decompaction of the polymers. Total internal reflection fluorescence spectroscopy (TIRF) was employed to evaluate the accessibility of βCD cavities to the fluorescent probe 2-anilinonaphthalene-6-sulfonic acid. Only a minor fraction of the βCD cavities was accessible in the thicker and less dense films; however, accessibility was largely improved with increased ionic strength using NaCl up to 1 M. Antifouling properties of the βCD dextran polymer films were assessed by TIRF real-time monitoring, using bovine serum albumin as a model protein, and showed a 5- to 10-fold reduction in nonspecific adsorption as compared to a bare quartz surface with the degree of reduction reflecting film thickness and interfacial polymer density.