| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Verne, Enrica
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (22/22 displayed)
- 2023UV-Cured Bio-Based Acrylated Soybean Oil Scaffold Reinforced with Bioactive Glassescitations
- 2023PMMA composite bone cement containing bioactive and ferrimagnetic glass-ceramic particles: Effect of temperature and of the additional phase on some physical and mechanical propertiescitations
- 2022In situ reduction of Ag on magnetic nanoparticles with gallic acid: effect of the synthesis parameters on morphologycitations
- 2021Surface Modification of Bioresorbable Phosphate Glasses for Controlled Protein Adsorptioncitations
- 2021Surface Modification of Bioresorbable Phosphate Glasses for Controlled Protein Adsorptioncitations
- 2017Composite bone cements for hyperthermia: modeling and characterization of magnetic, calorimetric and in vitro heating propertiescitations
- 2015Development and Characterization of PEEK/B2O3-Doped 45S5 Bioactive Glass Composite Coatings Obtained by Electrophoretic Depositioncitations
- 2014Composite bone cements loaded with a bioactive and ferrimagnetic glass-ceramic. Part I: Morphological, mechanical and calorimetric characterizationcitations
- 2013Development of PMMA bone cement loaded with a ferrimagnetic bioactive glass ceramic for hypethermia treatment
- 2013New PMMA bone cement added with ferrimagnetic bioactive glass for hyperthermia treatment
- 2013Antibiotic loading on bioactive glasses and glass-ceramics: an approach to surface modificationcitations
- 2012Bioactive glass-derived trabecular coating: a smart solution for enhancing osteointegration of prosthetic elementscitations
- 2009Micro-CT studies on 3-D bioactive glass-ceramic scaffolds for bone regenerationcitations
- 2008Synthesis and Characterization of MCM-41 spheres inside bioactive glass-ceramic scaffoldcitations
- 2008Surface Functionalisation of biomaterials with alkaline phosphatase
- 2007Fabrication and characterisation of Bioglass®-based glass-ceramic foam scaffolds for tissue engineering
- 2005Polymerization shrinkage for a novel dental composite with polymeric matrix
- 2005Surface treatment on an implant cobalt alloy for high biocompatibility and wear resistancecitations
- 2004Double-layer glass-ceramic coatings on Ti6Al4V for dental implants
- 2004Silver containing bioactive glasses prepared by molten salt ion-exchangecitations
- 2002Correlation between microstructure and properties of biocomposite coatings
- 2000Glass-matrix biocomposites: synthesis and characterisation
Places of action
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article
Surface Modification of Bioresorbable Phosphate Glasses for Controlled Protein Adsorption
Abstract
<p>The traditional silicate bioactive glasses exhibit poor thermal processability, which inhibits fiber drawing or sintering into scaffolds. The composition of the silicate glasses has been modified to enable hot processing. However, the hot forming ability is generally at the expense of bioactivity. Metaphosphate glasses, on the other hand, possess excellent thermal processability, congruent dissolution, and a tailorable degradation rate. However, due to the layer-by-layer dissolution mechanism, cells do not attach to the material surface. Furthermore, the congruent dissolution leads to a low density of OH groups forming on the glass surface, limiting the adsorption of proteins. It is well regarded that the initial step of protein adsorption is critical as the cells interact with this protein layer, rather than the biomaterial itself. In this paper, we explore the possibility of improving protein adsorption on the surface of phosphate glasses through a variety of surface treatments, such as washing the glass surface in acidic (pH 5), neutral, and basic (pH 9) buffer solutions followed or not by a treatment with (3-aminopropyl)triethoxysilane (APTS). The impact of these surface treatments on the surface chemistry (contact angle, ζ-potential) and glass structure (FTIR) was assessed. In this manuscript, we demonstrate that understanding of the material surface chemistry enables to selectively improve the adsorption of albumin and fibronectin (used as model proteins). Furthermore, in this study, well-known silicate bioactive glasses (i.e., S53P4 and 13-93) were used as controls. While surface treatments clearly improved proteins adsorption on the surface of both silicate and phosphate glasses, it is of interest to note that protein adsorption on phosphate glasses was drastically improved to reach similar protein grafting ability to the silicate bioactive glasses. Overall, this study demonstrates that the limited cell/phosphate glass biological response can easily be overcome through deep understanding and control of the glass surface chemistry. </p>