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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Tanaka, Manabu
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Topics
Publications (10/10 displayed)
- 2024Synthesis of ternary titanium–niobium nitride nanoparticles by induction thermal plasma
- 2022Numerical Analysis of Metal Transfer Process in Plasma MIG Weldingcitations
- 2021Effect of alkaline elements on the metal transfer behavior in metal cored arc weldingcitations
- 2021Relationship among welding defects with convection and material flow dynamic considering principal forces in plasma arc weldingcitations
- 2020Numerical study of the metal vapour transport in tungsten inert-gas welding in argon for stainless steelcitations
- 2020Numerical study of the effects and transport mechanisms of iron vapour in tungsten inert-gas welding in argoncitations
- 2020Multiwall Carbon Nanotube Composites as Artificial Joint Materials.citations
- 2018A computational model of gas tungsten arc welding of stainless steel: the importance of treating the different metal vapours simultaneouslycitations
- 2017Mixing of multiple metal vapours into an arc plasma in gas tungsten arc welding of stainless steelcitations
- 2015Numerical analysis of fume formation mechanism in TIG weldingcitations
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article
Multiwall Carbon Nanotube Composites as Artificial Joint Materials.
Abstract
Because ultrahigh-molecular-weight polyethylene (UHMWPE) is susceptible to frictional wear when used in sliding members of artificial joints, it is common practice to use cross-linked UHMWPE instead. However, cross-linked UHMWPE has low impact resistance; implant breakage has been reported in some cases. Hence, sliding members of artificial joints pose a major trade-off between wear resistance and impact resistance, which has not been resolved by any UHMWPE. On the other hand, multiwall carbon nanotubes (MWCNTs) are used in industrial products for reinforcement of polymeric materials but not used as biomaterials because of their unclear safety. In the present study, we attempted to solve this trade-off issue by complexing UHMWPE with MWCNTs. In addition, we assessed the safety of these composites for use in sliding members of artificial joints. The results showed the equivalence of MWCNT/UHMWPE composites to cross-linked UHMWPE in terms of wear resistance and to non-cross-linked UHMWPE in terms of impact resistance. In addition, all MWCNT/UHMWPE composites examined complied with the requirements of biosafety testing in accordance with the ISO10993-series specifications for implantable medical devices. Furthermore, because MWCNTs can occur alone in wear dust, MWCNTs in an amount of about 1.5 times that contained in the dust produced from 50 years of wear (in the worst case) were injected into rat knees, which were monitored for 26 weeks. Although mild inflammatory reactions occurred in the joints, the reactions soon became quiescent. In addition, the MWCNTs did not migrate to other organs. Furthermore, MWCNTs did not exhibit carcinogenicity when injected into the knees of mice genetically modified to spontaneously develop cancer. The MWCNT/UHMWPE composite is a new biomaterial expected to be safe for clinical applications in both total hip arthroplasty and total knee arthroplasty as the first sliding member of artificial joints to have both high wear resistance and high impact resistance.