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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Peplińska, Barbara
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2021Nanocellulose Production Using Ionic Liquids with Enzymatic Pretreatmentcitations
- 2020Nanocomposite Gel as Injectable Therapeutic Scaffold: Microstructural Aspects and Bioactive Propertiescitations
- 2019Fluorescein ether-ester dyes for labeling of fluorinated methacrylate nanoparticlescitations
- 2018Silver and ultrasmall iron oxides nanoparticles in hydrocolloids: Effect of magnetic field and temperature on self-organizationcitations
- 2018Nano-multilayered coatings of (TiAlSiY)N/MeN (Me=Mo, Cr and Zr): Influence of composition of the alternating layer on their structural and mechanical propertiescitations
- 2018Gel with silver and ultrasmall iron oxide nanoparticles produced with Amanita muscaria extract: physicochemical characterization, microstructure analysis and anticancer propertiescitations
- 2018ZnS coating for enhanced environmental stability and improved properties of ZnO thin filmscitations
- 2017Self-organizing silver and ultrasmall iron oxide nanoparticles prepared with ginger rhizome extract: Characterization, biomedical potential and microstructure analysis of hydrocolloidscitations
- 2017Release and cytotoxicity studies of magnetite/Ag/antibiotic nanoparticles: An interdependent relationshipcitations
- 2016Gradient nanostructured coatings obtained by magnetron sputtering of a multiphase AlN–TiB<inf>2</inf>–TiSi<inf>2</inf> targetcitations
- 2016Fourier transform infrared and Raman spectroscopy studies on magnetite/Ag/antibiotic nanocompositescitations
- 2016High temperature behavior of functional TiAlBSiN nanocomposite coatingscitations
- 2015Synthesis and characterization of magnetite/silver/antibiotic nanocomposites for targeted antimicrobial therapycitations
- 2015Atomic layer deposition TiO2 coated porous silicon surface: Structural characterization and morphological featurescitations
Places of action
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article
Nanocomposite Gel as Injectable Therapeutic Scaffold: Microstructural Aspects and Bioactive Properties
Abstract
<p>The development of tissue scaffolds able to provide proper and accelerated regeneration of tissue is a main task of tissue engineering. We developed a nanocomposite gel that may be used as an injectable therapeutic scaffold. The nanocomposite gel is based on biocompatible gelling agents with embedded nanoparticles (iron oxide, silver, and hydroxyapatite) providing therapeutic properties. We have investigated the microstructure of the nanocomposite gel exposed to different substrates (porous materials and biological tissue). Here we show that the nanocomposite gel has the ability to self-reassemble mimicking the substrate morphology: exposition on porous mineral substrate caused reassembling of nanocomposite gel into 10× smaller scale structure; exposition to a section of humerus cortical bone decreased the microstructure scale more than twice (to ≤3 μm). The reassembling happens through a transitional layer which exists near the phase separation boundary. Our results impact the knowledge of gels explaining their abundance in biological organisms from the microstructural point of view. The results of our biological experiments showed that the nanocomposite gel may find diverse applications in the biomedical field.</p>