| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
| |
| Motta, Antonella |
| |
| Aletan, Dirar |
| |
| Mohamed, Tarek |
| |
| Ertürk, Emre |
| |
| Taccardi, Nicola |
| |
| Kononenko, Denys |
| |
| Petrov, R. H. | Madrid |
|
| Alshaaer, Mazen | Brussels |
|
| Bih, L. |
| |
| Casati, R. |
| |
| Muller, Hermance |
| |
| Kočí, Jan | Prague |
|
| Šuljagić, Marija |
| |
| Kalteremidou, Kalliopi-Artemi | Brussels |
|
| Azam, Siraj |
| |
| Ospanova, Alyiya |
| |
| Blanpain, Bart |
| |
| Ali, M. A. |
| |
| Popa, V. |
| |
| Rančić, M. |
| |
| Ollier, Nadège |
| |
| Azevedo, Nuno Monteiro |
| |
| Landes, Michael |
| |
| Rignanese, Gian-Marco |
|
Kosel, Jürgen
Laboratori Guglielmo Marconi (Italy)
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (32/32 displayed)
- 2018Development of printed sensors for shoe sensing applicationscitations
- 2017Magnetic composite Hydrodynamic Pump with Laser Induced Graphene Electrodescitations
- 2017Sensing system for salinity testing using laser-induced graphene sensorscitations
- 2017Current induced domain wall motion in cylindrical nanowires
- 2017Scalable high-affinity stabilization of magnetic iron oxide nanostructures by a biocompatible antifouling homopolymercitations
- 2016Magnetically Triggered Monodispersed Nanocomposite Fabricated by Microfluidic Approach for Drug Deliverycitations
- 2016A Magnetoresistive Tactile Sensor for Harsh Environment Applicationscitations
- 2016Piezoelectric transducer array microspeakercitations
- 2016Highly Efficient Thermoresponsive Nanocomposite for Controlled Release Applicationscitations
- 2016Flexible carbon nanotube nanocomposite sensor for multiple physiological parameter monitoringcitations
- 2016Magnetic Nanocomposite Cilia Energy Harvestercitations
- 2016Fabrication and characterization of magnetic composite membrane pressure sensorcitations
- 2016Tunable magnetic nanowires for biomedical and harsh environment applicationscitations
- 2016A single magnetic nanocomposite cilia force sensorcitations
- 2016Magnetic nanocomposite sensor
- 2016Magnetic Tactile Sensor for Braille Readingcitations
- 2015Magnetic Nanocomposite Cilia Tactile Sensorcitations
- 2015Biomimetic magnetic nanocomposite for smart skinscitations
- 2015Magnetoelectric polymer nanocomposite for flexible electronicscitations
- 2015Fabrication and properties of multiferroic nanocomposite filmscitations
- 2015Electromagnetically powered electrolytic pump and thermo-responsive valve for drug deliverycitations
- 2015Magnetic micropillar sensors for force sensingcitations
- 2015Rapid and molecular selective electrochemical sensing of phthalates in aqueous solutioncitations
- 2015Osmotically driven drug delivery through remote-controlled magnetic nanocomposite membranescitations
- 2014Magnetic polymer nanocomposites for sensing applicationscitations
- 2014Introducing molecular selectivity in rapid impedimetric sensing of phthalatescitations
- 2014A magnetic nanocomposite for biomimetic flow sensingcitations
- 2013Fabrication and properties of SmFe2-PZT magnetoelectric thin filmscitations
- 2013Integrated passive and wireless sensor for magnetic fields, temperature and humiditycitations
- 2013Technique for rapid detection of phthalates in water and beveragescitations
- 2012Microfabrication of magnetostrictive beams based on NiFe film doped with B and Mo for integrated sensor systemscitations
- 2012Optimization of autonomous magnetic field sensor consisting of giant magnetoimpedance sensor and surface acoustic wave transducercitations
Places of action
| Organizations | Location | People |
|---|
article
Scalable high-affinity stabilization of magnetic iron oxide nanostructures by a biocompatible antifouling homopolymer
Abstract
Iron oxide nanostructures have been widely developed for biomedical applications, due to their magnetic properties and biocompatibility. In clinical application, the stabilization of these nanostructures against aggregation and non-specific interactions is typically achieved using weakly anchored polysaccharides, with better-defined and more strongly anchored synthetic polymers not commercially adopted due to complexity of synthesis and use. Here, we show for the first time stabilization and biocompatibilization of iron oxide nanoparticles by a synthetic homopolymer with strong surface anchoring and a history of clinical use in other applications, poly(2-methacryloyloxyethy phosphorylcholine) (poly(MPC)). For the commercially important case of spherical particles, binding of poly(MPC) to iron oxide surfaces and highly effective individualization of magnetite nanoparticles (20 nm) are demonstrated. Next-generation highaspect ratio nanowires (both magnetite/maghemite and core-shell iron/iron oxide) are furthermore stabilized by poly(MPC)-coating, with nanowire cytotoxicity at large concentrations significantly reduced. The synthesis approach is exploited to incorporate functionality into the poly(MPC) chain is demonstrated by random copolymerization with an alkyne-containing monomer for click-chemistry. Taking these results together, poly(MPC) homopolymers and random copolymers offer a significant improvement over current iron oxide nanoformulations, combining straightforward synthesis, strong surface-anchoring and well-defined molecular weight.