| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Tan, Jin-Chong
University of Oxford
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (6/6 displayed)
- 2023Stress–strain relationships and yielding of metal-organic framework monolithscitations
- 2022Sol-gel processing of a covalent organic framework for the generation of hierarchically porous monolithic adsorbentscitations
- 2021Multifaceted study of the interactions between CPO-27-Ni and polyurethane and their impact on nitric oxide release performancecitations
- 2020MOF-based polymeric nanocomposite films as potential materials for drug delivery devices in ocular therapeuticscitations
- 2020Multifaceted study of the interactions between CPO-27-Ni and polyurethane and their impact on nitric oxide release performancecitations
- 2019Polymer nanocomposites functionalised with nanocrystals of zeolitic imidazolate frameworks as ethylene control agentscitations
Places of action
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article
Multifaceted study of the interactions between CPO-27-Ni and polyurethane and their impact on nitric oxide release performance
Abstract
A multifaceted study involving focused ion beam scanning electron microscopy techniques, mechanical analysis, water adsorption measurements, and molecular simulations is employed to rationalize the nitric oxide release performance of polyurethane films containing 5, 10, 20, and 40 wt % of the metal-organic framework (MOF) CPO-27-Ni. The polymer and the MOF are first demonstrated to exhibit excellent compatibility. This is reflected in the even distribution and encapsulation of large wt % MOF loadings throughout the full thickness of the films and by the rather minimal influence of the MOF on the mechanical properties of the polymer at low wt %. The NO release efficiency of the MOF is attenuated by the polymer and found to depend on wt % of MOF loading. The formation of a fully connected network of MOF agglomerates within the films at higher wt % is proposed to contribute to a more complex guest transport in these formulations, resulting in a reduction of NO release efficiency and film ductility. An optimum MOF loading of 10 wt % is identified for maximizing NO release without adversely impacting the polymer properties. Bactericidal efficacy of released NO from the films is demonstrated against Pseudomonas aeruginosa, with a >8 log10 reduction in cell density observed after a contact period of 24 h.