| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Skirtach, Andre
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (22/22 displayed)
- 2024Insights in the structural hierarchy of statically crystallized palm oilcitations
- 2024Insights in the structural hierarchy of statically crystallized palm oilcitations
- 2024From nucleation to fat crystal network : effects of stearic-palmitic sucrose ester on static crystallization of palm oilcitations
- 2024Ratiometric dual-emitting thermometers based on rhodamine B dye-incorporated (nano) curcumin periodic mesoporous organosilicas for bioapplicationscitations
- 2022The influence of Ca/Mg ratio on autogelation of hydrogel biomaterials with bioceramic compoundscitations
- 2022Improving green Yb3+/Er3+ upconversion luminescence by co-doping metal ions into an oxyfluoride matrix
- 2022Hybrid lanthanide-doped rattle-type thermometers for theranosticscitations
- 2022Hybrid NaYF4:Er,Yb@NaYF4@nano-MOF@AuNPs@LB composites for Yb3+-Er3+ physiological thermometrycitations
- 2022The influence of bases on thermal decomposition synthesis of LaF3
- 2021Hydrothermal synthesis of barium titanate nano/microrods and particle agglomerates using a sodium titanate precursorcitations
- 2021Combining fat and waxes in hybrid systems for bakery application
- 2020Temperature Window for Encapsulation of an Enzyme into Thermally Shrunk, CaCO3 Templated Polyelectrolyte Multilayer Capsules.citations
- 2020Temperature window for encapsulation of an enzyme into thermally shrunk, CaCO3 templated polyelectrolyte multilayer capsulescitations
- 2020Alkaline phosphatase delivery system based on calcium carbonate carriers for acceleration of ossificationcitations
- 2020Alkaline phosphatase delivery system based on calcium carbonate carriers for acceleration of ossificationcitations
- 2019Piezoelectric 3-D fibrous poly(3-hydroxybutyrate)-based scaffolds ultrasound-mineralized with calcium carbonate for bone tissue engineering : inorganic phase formation, osteoblast cell adhesion, and proliferationcitations
- 2019The effect of hybrid coatings based on hydrogel, biopolymer and inorganic components on the corrosion behavior of titanium bone implants.citations
- 2018Nanostructured biointerfaces based on bioceramic calcium carbonate/hydrogel coatings on titanium with an active enzyme for stimulating osteoblasts growthcitations
- 2012Control of cell adhesion by mechanical reinforcement of soft polyelectrolyte films with nanoparticlescitations
- 2011Neuron cells uptake of polymeric microcapsules and subsequent intracellular releasecitations
- 2011Release properties of pressurized microgel templated capsulescitations
- 2006Preparation of polyelectrolyte microcapsules with silver and gold nanoparticles in a shell and the remote destruction of microcapsules under laser irradiationcitations
Places of action
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article
Alkaline phosphatase delivery system based on calcium carbonate carriers for acceleration of ossification
Abstract
Composite bioceramic and hydrogel-based containers harboring alkaline phosphatase are generated through encapsulation of this enzyme by its immobilization into CaCO3-based bioceramic materials in combination with a hydrogel assembly technique and subsequent gelification. A refined way of synthesis and modification allows preparing the enzyme delivery system with functionalized protection layers. The particles are characterized by electron microscopy, Fourier transform infrared (FTIR) spectroscopy, and enzyme activity measurements. Loading efficiency and loading capacity are investigated depending on particle size, time of enzyme loading, and various container compositions and enzyme concentrations. Our results reveal that the size of particles influences their morphology and this, in turn, affects the activity of the encapsulated enzymes. Various functionalizations of the surfaces, including protection by the hydrogel layer, formation of hollow silver alginate, or calcium alginate encapsulation, decrease the enzymatic activity. The presence of a good therapeutic effect on osteoblastic cells coupled with a relatively high loading capacity, biocompatibility, and ease of fabrication suggests that the developed carriers are promising candidates for efficient drug delivery, especially in the field of bone reconstruction.