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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Zhang, Hongbo
Åbo Akademi University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (8/8 displayed)
- 2023Influence of Chain Length of Gradient and Block Copoly(2-oxazoline)s on Self-Assembly and Drug Encapsulationcitations
- 2022Influence of chain length of gradient and block copoly(2-oxazoline)s on self-assembly and drug encapsulationcitations
- 2022Microfluidic-Assisted Fabrication of Dual-Coated pH-Sensitive Mesoporous Silica Nanoparticles for Protein Deliverycitations
- 2022Influence of Chain Length of Gradient and Block Copoly(2-oxazoline)s on Self-Assembly and Drug Encapsulationcitations
- 2022Influence of Chain Length of Gradient and Block Copoly(2‐oxazoline)s on Self‐Assembly and Drug Encapsulationcitations
- 2017Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitationcitations
- 2017Microfluidics platform for glass capillaries and its application in droplet and nanoparticle fabricationcitations
- 2015Microfluidic Nanoprecipitation of a Stimuli Responsive Hybrid Nanocomposite for Antitumoral Applications
Places of action
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article
Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitation
Abstract
<p>Although a number of techniques exist for generating structured organic nanocomposites, it is still challenging to fabricate them in a controllable, yet universal and scalable manner. In this work, a microfluidic platform, exploiting superfast (milliseconds) time intervals between sequential nanoprecipitation processes, has been developed for high-throughput production of structured core/shell nanocomposites. The extremely short time interval between the sequential nanoprecipitation processes, facilitated by the multiplexed microfluidic design, allows us to solve the instability issues of nanocomposite cores without using any stabilizers. Beyond high throughput production rate (similar to 700 g/day on a single device), the generated core/shell nanocomposites harness the inherent ultrahigh drug loading degree and enhanced payload dissolution kinetics of drug nanocrystals and the controlled drug release from polymer-based nanopartides.</p>