| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Österberg, Monika
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (26/26 displayed)
- 2024Biodegradation of Lignocellulose-Polyester Composite Films in Freshwater and Seawater Conditionscitations
- 2024Adsorption of sulphonated lignin-carbohydrate complexes (LCCs) onto cellulose surfaces
- 2024Hydrophobized lignin nanoparticle-stabilized Pickering foams : building blocks for sustainable lightweight porous materialscitations
- 2023Characterization of cell-biomaterial adhesion forces that influence 3D cell culture
- 2022Durable Biopolymer Films From Lignin-Carbohydrate Complex Derived From a Pulp Mill Side Streamcitations
- 2022Hybrid films from cellulose nanomaterials—properties and defined optical patternscitations
- 2021Durable Biopolymer Films From Lignin-Carbohydrate Complex Derived From a Pulp Mill Side Streamcitations
- 2021Cellulose nanofibers/lignin particles/tragacanth gum nanocomposite hydrogels for biomedical applications
- 2021Colloidal Lignin Particles and Epoxies for Bio-Based, Durable, and Multiresistant Nanostructured Coatingscitations
- 2021Tuning the functional properties of lignocellulosic films by controlling the molecular and supramolecular structure of lignincitations
- 2021Toward waste valorization by converting bioethanol production residues into nanoparticles and nanocomposite filmscitations
- 2020Three-Dimensional Printed Cell Culture Model Based on Spherical Colloidal Lignin Particles and Cellulose Nanofibril-Alginate Hydrogelcitations
- 2020Three-Dimensional Printed Cell Culture Model Based on Spherical Colloidal Lignin Particles and Cellulose Nanofibril-Alginate Hydrogelcitations
- 2020Observing microfibril bundles in wood by small-angle neutron scattering
- 2020Bundling of cellulose microfibrils in native and polyethylene glycol-containing wood cell walls revealed by small-angle neutron scatteringcitations
- 2020Moisture-related changes in the nanostructure of woods studied with X-ray and neutron scatteringcitations
- 2019Understanding hemicellulose-cellulose interactions in cellulose nanofibril-based compositescitations
- 2019Small-angle scattering model for efficient characterization of wood nanostructure and moisture behaviourcitations
- 2019Strong, Ductile, and Waterproof Cellulose Nanofibril Composite Films with Colloidal Lignin Particlescitations
- 2017Layer-by-layer assembled hydrophobic coatings for cellulose nanofibril films and textiles, made of polylysine and natural wax particles
- 2017Adsorption of Proteins on Colloidal Lignin Particles for Advanced Biomaterialscitations
- 2016Electrochemical detection of hydrogen peroxide on platinum-containing tetrahedral amorphous carbon sensors and evaluation of their biofouling propertiescitations
- 2015Correlation between cellulose thin film supramolecular structures and interactions with watercitations
- 2015Electrochemical detection of hydrogen peroxide on platinum-containing tetrahedral amorphous carbon sensors and evaluation of their biofouling propertiescitations
- 2013Non-ionic assembly of nanofibrillated cellulose and polyethylene glycol grafted carboxymethyl cellulose and the effect of aqueous lubrication in nanocomposite formationcitations
- 2012Interactions between inorganic nanoparticles and cellulose nanofibrilscitations
Places of action
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article
Three-Dimensional Printed Cell Culture Model Based on Spherical Colloidal Lignin Particles and Cellulose Nanofibril-Alginate Hydrogel
Abstract
<p>Three-dimensional (3D) printing has been an emerging technique to fabricate precise scaffolds for biomedical applications. Cellulose nanofibril (CNF) hydrogels have attracted considerable attention as a material for 3D printing because of their shear-thinning properties. Combining cellulose nanofibril hydrogels with alginate is an effective method to enable cross-linking of the printed scaffolds in the presence of Ca2+ ions. In this work, spherical colloidal lignin particles (CLPs, also known as spherical lignin nanoparticles) were used to prepare CNF-alginate-CLP nanocomposite scaffolds. High-resolution images obtained by atomic force microscopy (AFM) showed that CLPs were homogeneously mixed with the CNF hydrogel. CLPs brought antioxidant properties to the CNF-alginate-CLP scaffolds in a concentration-dependent manner and increased the viscosity of the hydrogels at a low shear rate, which correspondingly provide better shape fidelity and printing resolution to the scaffolds. Interestingly, the CLPs did not affect the viscosity at high shear rates, showing that the shear thinning behavior typical for CNF hydrogels was retained, enabling easy printing. The CNF-alginate-CLP scaffolds demonstrated shape stability after printing, cross-linking, and storage in Dulbecco's phosphate buffer solution (DPBS +) containing Ca2+ and Mg2+ ions, up to 7 days. The 3D-printed scaffolds showed relative rehydration ratio values above 80% after freeze-drying, demonstrating a high water-retaining capability. Cell viability tests using hepatocellular carcinoma cell line HepG2 showed no negative effect of CLPs on cell proliferation. Fluorescence microscopy indicated that HepG2 cells grew not only on the surfaces but also inside the porous scaffolds. Overall, our results demonstrate that nanocomposite CNF-alginate-CLP scaffolds have high potential in soft-tissue engineering and regenerative-medicine applications.</p>