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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Kumar, Ashok
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (21/21 displayed)
- 2023Strontium-Substituted Nanohydroxyapatite-Incorporated Poly(lactic acid) Composites for Orthopedic Applications: Bioactive, Machinable, and High-Strength Propertiescitations
- 2023Sb2Se3 Nanosheet Film-Based Devices for Ultraviolet Photodetection and Resistive Switchingcitations
- 2023Design consideration and recent developments in flexible, transparent and wearable antenna technology: A reviewcitations
- 2021Effect of Wheat Straw Ash on Fresh and Hardened Concrete Reinforced with Jute Fibercitations
- 2020Improved Bone Regeneration in Rabbit Bone Defects Using 3D Printed Composite Scaffolds Functionalized with Osteoinductive Factorscitations
- 2020Tin titanate – the hunt for a new ferroelectric perovskitecitations
- 2019Tin titanate – the hunt for a new ferroelectric perovskitecitations
- 2018Optically controlled polarization in highly oriented ferroelectric thin filmscitations
- 2017Optically controlled polarization in highly oriented ferroelectric thin filmscitations
- 2017Palladium-based ferroelectrics and multiferroics:theory and experimentcitations
- 2017Palladium-based ferroelectrics and multiferroics : theory and experimentcitations
- 2016Effect of thickness on dielectric, ferroelectric, and optical properties of Ni substituted Pb(Zr0.2Ti0.8)O3 thin filmscitations
- 2015Effect of thickness on dielectric, ferroelectric, and optical properties of Ni substituted Pb(Zr 0.2 Ti 0.8 )O 3 thin filmscitations
- 2014Dynamic nanocrystal response and high temperature growth of carbon nanotube-ferroelectric hybrid nanostructurecitations
- 2014Faceting oscillations in nano-ferroelectricscitations
- 2013Compositional engineering of BaTiO3/(Ba,Sr)TiO3 ferroelectric superlatticescitations
- 2012Magnon Raman spectroscopy and in-plane dielectric response in BiFeO3:Relation to the Polomska transitioncitations
- 2012Ferroelectric and Dielectric Properties of BaTiO3/Ba0.30Sr0.70TiO3 Superlatticescitations
- 2010Magnetic effects on dielectric and polarization behavior of multiferroic heterostructurescitations
- 2010Evaluation of boronate-containing polymer brushes and gels as substrates for carbohydrate-mediated adhesion and cultivation of animal cells.citations
- 2010Fabrication and characterization of the multiferroic birelaxor lead-iron-tungstate/lead-zirconate-titanatecitations
Places of action
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article
Strontium-Substituted Nanohydroxyapatite-Incorporated Poly(lactic acid) Composites for Orthopedic Applications: Bioactive, Machinable, and High-Strength Properties
Abstract
Traditional metal-alloy bone fixation devices provide structural support for bone repair but have limitations in actively promoting bone healing and often require additional surgeries for implant removal. In this study, we focused on addressing these challenges by fabricating biodegradable composites using poly(lactic acid) (PLA) and strontium-substituted nanohydroxyapatite (SrHAP) via melt compounding and injection molding. Various percentages of SrHAP (5, 10, 20, and 30% w/w) were incorporated into the PLA matrix. We systematically investigated the structural, morphological, thermal, mechanical, rheological, and dynamic mechanical properties of the prepared composites. Notably, the tensile modulus, a critical parameter for orthopedic implants, significantly improved from 2.77 GPa in pristine PLA to 3.73 GPa in the composite containing 10% w/w SrHAP. The incorporation of SrHAP (10% w/w) into the PLA matrix led to an increased storage modulus, indicating a uniform dispersion of SrHAP within the PLA and good compatibility between the polymer andnanoparticles. Moreover, we successfully fabricated screws using PLA composites with 10% (w/w) SrHAP, demonstrating their formability at room temperature and radiopacity when observed under X-ray microtomography (micro-CT). Furthermore, the water contact angle decreased from 93 ± 2° for pristine PLA to 75 ± 3° for the composite containing SrHAP, indicating better surface wettability. To assess the biological behavior of the composites, we conducted in vitro cell-material tests, which confirmed their osteoconductive and osteoinductive properties. These findings highlight the potential of our developed PLA/SrHAP10 (10% w/w) composites as machinable implant materials for orthopedic applications. In conclusion, our study presents the fabrication and comprehensive characterization of biodegradable composites comprising PLA and strontium-substituted nanohydroxyapatite (SrHAP). These composites exhibit improved mechanical properties, formability, and radiopacity while also demonstrating desirable biological behavior. Our results suggest that these PLA/SrHAP10 composites hold promise as machinable implant materials for orthopedic applications.