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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Baniasadi, Hossein
Aalto University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (21/21 displayed)
- 2024Polypyrrole-modified flax fiber sponge impregnated with fatty acids as bio-based form-stable phase change materials for enhanced thermal energy storage and conversioncitations
- 2024Polypyrrole-modified flax fiber sponge impregnated with fatty acids as bio-based form-stable phase change materials for enhanced thermal energy storage and conversioncitations
- 2024Fabrication of biocomposite materials with polycaprolactone and activated carbon extracted from agricultural wastecitations
- 2024Exploring the potential of regenerated Ioncell fiber composites: a sustainable alternative for high-strength applicationscitations
- 2024Elucidating the enduring transformations in cellulose-based carbon nanofibers through prolonged isothermal treatmentcitations
- 2024Wood flour and Kraft lignin enable air-drying of the nanocellulose-based 3D-printed structurescitations
- 2024Recycled carbon fiber reinforced composites: Enhancing mechanical properties through co-functionalization of carbon nanotube-bonded microfibrillated cellulosecitations
- 2024A cradle-to-gate life cycle assessment of polyamide-starch biocomposites: carbon footprint as an indicator of sustainabilitycitations
- 2023Strontium-Substituted Nanohydroxyapatite-Incorporated Poly(lactic acid) Composites for Orthopedic Applications: Bioactive, Machinable, and High-Strength Propertiescitations
- 2023Flexible and conductive nanofiber textiles for leakage-free electro-thermal energy conversion and storagecitations
- 2023Heat-Induced Actuator Fibers: Starch-Containing Biopolyamide Composites for Functional Textilescitations
- 2023High-concentration lignin biocomposites with low-melting point biopolyamidecitations
- 2023Innovative integration of pyrolyzed biomass into polyamide 11: Sustainable advancements through in situ polymerization for enhanced mechanical, thermal, and additive manufacturing propertiescitations
- 2021Exfoliated clay nanocomposites of renewable long-chain aliphatic polyamide through in-situ polymerizationcitations
- 2021Sustainable composites of surface-modified cellulose with low-melting point polyamidecitations
- 2021Novel long-chain aliphatic polyamide/surface-modified silicon dioxide nanocomposites: in-situ polymerization and propertiescitations
- 2021Alginate/cartilage extracellular matrix-based injectable interpenetrating polymer network hydrogel for cartilage tissue engineeringcitations
- 2021Selective Laser Sintering of Lignin-Based Compositescitations
- 20213D-Printed Thermoset Biocomposites Based on Forest Residues by Delayed Extrusion of Cold Masterbatch (DECMA)citations
- 2021High-Performance and Biobased Polyamide/Functionalized Graphene Oxide Nanocomposites through In Situ Polymerization for Engineering Applicationscitations
- 2015Investigation of thermomechanical properties of UHMWPE/graphene oxide nanocomposites prepared by in situ Ziegler–Natta polymerizationcitations
Places of action
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article
Strontium-Substituted Nanohydroxyapatite-Incorporated Poly(lactic acid) Composites for Orthopedic Applications: Bioactive, Machinable, and High-Strength Properties
Abstract
Traditional metal-alloy bone fixation devices provide structural support for bone repair but have limitations in actively promoting bone healing and often require additional surgeries for implant removal. In this study, we focused on addressing these challenges by fabricating biodegradable composites using poly(lactic acid) (PLA) and strontium-substituted nanohydroxyapatite (SrHAP) via melt compounding and injection molding. Various percentages of SrHAP (5, 10, 20, and 30% w/w) were incorporated into the PLA matrix. We systematically investigated the structural, morphological, thermal, mechanical, rheological, and dynamic mechanical properties of the prepared composites. Notably, the tensile modulus, a critical parameter for orthopedic implants, significantly improved from 2.77 GPa in pristine PLA to 3.73 GPa in the composite containing 10% w/w SrHAP. The incorporation of SrHAP (10% w/w) into the PLA matrix led to an increased storage modulus, indicating a uniform dispersion of SrHAP within the PLA and good compatibility between the polymer andnanoparticles. Moreover, we successfully fabricated screws using PLA composites with 10% (w/w) SrHAP, demonstrating their formability at room temperature and radiopacity when observed under X-ray microtomography (micro-CT). Furthermore, the water contact angle decreased from 93 ± 2° for pristine PLA to 75 ± 3° for the composite containing SrHAP, indicating better surface wettability. To assess the biological behavior of the composites, we conducted in vitro cell-material tests, which confirmed their osteoconductive and osteoinductive properties. These findings highlight the potential of our developed PLA/SrHAP10 (10% w/w) composites as machinable implant materials for orthopedic applications. In conclusion, our study presents the fabrication and comprehensive characterization of biodegradable composites comprising PLA and strontium-substituted nanohydroxyapatite (SrHAP). These composites exhibit improved mechanical properties, formability, and radiopacity while also demonstrating desirable biological behavior. Our results suggest that these PLA/SrHAP10 composites hold promise as machinable implant materials for orthopedic applications.