| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Brunelle, Alain
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (19/19 displayed)
- 2023Chemical imaging of alligatoring oil paintings
- 2022TOF-SIMS Imaging of Biological Tissue Sections and Structural Determination Using Tandem MScitations
- 2021TOF-SIMS Imaging of Biological Tissue Sections and Structural Determination Using Tandem MScitations
- 2021Wax finishing in Roman polychrome statuary: Ganosis on the colossal head from Dougga (Tunisia)citations
- 2021Time-of-Flight Secondary Ion Mass Spectrometry Imaging of Cross Sections from the Bacchanals Paintings of Nicolas Poussincitations
- 2018Tandem MS Imaging and in Situ Characterization of Bioactive Wood Metabolites in Amazonian Tree Species Sextonia rubracitations
- 2018The Prismatic Layer of Pinna: A Showcase of Methodological Problems and Preconceived Hypothesescitations
- 2018Tandem Mass Spectrometry Imaging and in Situ Characterization of Bioactive Wood Metabolites in Amazonian Tree Species Sextonia rubracitations
- 2016Mapping Dicorynia guianensis Amsh. wood constituents by submicron resolution cluster-TOF-SIMS imagingcitations
- 2015Time-of-flight secondary ion mass spectrometry imaging of biological samples with delayed extraction for high mass and high spatial resolutionscitations
- 2014Cluster TOF-SIMS imaging as a tool for micrometric histology of lipids in tissue.
- 2013Localisation and quantification of benzalkonium chloride in eye tissue by TOF-SIMS imaging and liquid chromatography mass spectrometry.citations
- 2013Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients.citations
- 2013Lipidomic and Spatio-Temporal Imaging of Fat by Mass Spectrometry in Mice Duodenum during Lipid Digestion.citations
- 2012Cluster TOF-SIMS imaging of human skin remains: analysis of a South-Andean mummy sample.citations
- 2010Animal urine as painting materials in African rock art revealed by cluster ToF-SIMS mass spectrometry imaging.citations
- 2006Structural analysis of secondary ions by post-source decay in time-of-flight secondary ion mass spectrometrycitations
- 2005Lipid imaging by gold cluster time-of-flight secondary ion mass spectrometry : application to Duchenne muscular dystrophycitations
- 2005Biological tissue imaging with time-of-flight secondary ion mass spectrometry and cluster ion sourcescitations
Places of action
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article
Tandem Mass Spectrometry Imaging and in Situ Characterization of Bioactive Wood Metabolites in Amazonian Tree Species Sextonia rubra
Abstract
Driven by a necessity for confident molecular identification at high spatial resolution, a new time-of-flight secondary ion mass spectrometry (TOF-SIMS) tandem mass spectrometry (tandem MS) imaging instrument has been recently developed. In this paper, the superior MS/MS spectrometry and imaging capability of this new tool is shown for natural product study. For the first time, via in situ analysis of the bioactive metabolites rubrenolide and rubrenolide in Amazonian tree species Sextonia rubra (Lauraceae), we were able both to analyze and to image by tandem MS the molecular products of natural biosynthesis. Despite the low abundance of the metabolites in the wood sample(s), efficient MS/MS analysis of these gamma-lactone compounds was achieved, providing high confidence in the identification and localization. In addition, tandem MS imaging minimized the mass interferences and revealed specific localization of these metabolites primarily in the ray parenchyma cells but also in certain oil cells and, further, revealed the presence of previously unidentified gamma-lactone, paving the way for future studies in biosynthesis.