• Deschamps, Julien

Abstract

<jats:title>Abstract</jats:title><jats:p>Soft bio-microcapsules are drops bounded by a thin elastic shell made of cross-linked proteins. Their shapes and their dynamics in flow depend on their membrane constitutive law characterized by shearing and area-dilatation resistance. The deformations of such capsules are investigated experimentally in planar elongation flows and compared with numerical simulations for three bidimensional models: Skalak, neo-Hookean and generalized Hooke. An original cross-flow microfluidic set-up allows the visualization of the deformed shape in the two perpendicular main fields of view. Whatever the elongation rate, the three semi-axis lengths of the ellipsoid fitting the experimental shape are measured up to 180 % of stretching of the largest axis. The geometrical analysis in the two views is sufficient to determine the constitutive law and the Poisson ratio of the membrane without a preliminary knowledge of the shear elastic modulus <jats:inline-formula><jats:alternatives><jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="gif" xlink:type="simple" xlink:href="S0022112015000695_inline1" /><jats:tex-math>$G_{s}$</jats:tex-math></jats:alternatives></jats:inline-formula>. We conclude that the membrane of human serum albumin capsules obeys the generalized Hooke law with a Poisson ratio of 0.4. The shear elastic modulus is then determined by the combination of numerical and experimental variations of the Taylor parameter with the capillary number.</jats:p>

Topics

• impedance spectroscopy
• simulation