| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Oliveira, Ana L.
Universidade Católica Portuguesa
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2022Adenosine-loaded silk fibroin aerogel particles for wound healing
- 2022Opening new avenues for bioceramicscitations
- 2021New prospects in skin regeneration and repair using nanophased hydroxyapatite embedded in collagen nanofiberscitations
- 2021High efficient strategy for the production of hydroxyapatite/silk sericin nanocompositescitations
- 2020Hydroxyapatite/sericin compositescitations
- 2020High efficient strategy for the production of hydroxyapatite/silk sericin nanocomposites
- 2020Hydroxyapatite/sericin composites:a simple synthesis route under near-physiological conditions of temperature and pH and preliminary study of the effect of sericin on the biomineralization processcitations
- 2019Sterile and dual-porous aerogels scaffolds obtained through a multistep supercritical CO2-based approachcitations
- 2019Sterile and dual-porous aerogels scaffolds obtained through a multistep supercritical CO 2 -based approachcitations
- 2018Combinatory approach for developing silk fibroin scaffolds for cartilage regenerationcitations
- 2017Modulating cell adhesion to polybutylene succinate biotextile constructs for tissue engineering applicationscitations
- 2017Silk-based anisotropical 3D biotextiles for bone regenerationcitations
- 2017Core-shell silk hydrogels with spatially tuned conformations as drug-delivery systemcitations
- 2016Combinatory approach for developing silk fibroin-based scaffolds with hierarchical porosity and enhanced performance for cartilage tissue engineering applications
- 2013Evaluation of novel 3D architectures based on knitting technologies for engineering biological tissues
- 2012Aligned silk-based 3-D architectures for contact guidance in tissue engineeringcitations
- 2009Nucleation and growth of biomimetic apatite layers on 3D plotted biodegradable polymeric scaffoldscitations
- 2005Study of the influence of β-radiation on the properties and mineralization of different starch-based biomaterialscitations
- 2004Pre-mineralisation of starch/polycrapolactone bone tissue engineering scaffolds by a calcium-silicate-based processcitations
- 2003Biomimetic coating of starch based polymeric foams produced by a calcium silicate based methodologycitations
- 2003Bi-composite sandwich moldingscitations
- 2003Sodium silicate gel as a precursor for the in vitro nucleation and growth of a bone-like apatite coating in compact and porous polymeric structurescitations
- 2001Sodium silicate gel induced self-mineralization of different compact and porous polymeric structurescitations
Places of action
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article
Sodium silicate gel as a precursor for the in vitro nucleation and growth of a bone-like apatite coating in compact and porous polymeric structures
Abstract
<p>In the present work, a new methodology to produce bioactive coatings on the surface of starch-based biodegradable polymers or other polymeric biomaterials is proposed. A sodium silicate gel is employed as an alternative nucleating agent to the more typical bioactive glasses for inducing the formation of a calcium-phosphate (Ca-P) layer. The method has the advantage of being able to coat efficiently both compact materials and porous 3D architectures aimed at being used on tissue replacement applications and as tissue engineering scaffolds. By means of this treatment, it is possible to observe the formation of an apatite-like layer, only after 6hours of simulated body fluid immersion. For the porous materials, this layer could also be observed inside the pores, clearly covering the cell walls. Furthermore, an increase of the surface hydrophilicity (higher amount of polar groups in the surface) might contribute to the formation of silanol groups that also act as apatite inductors. After 30 days of SBF immersion, the apatite-like films exhibit a partially amorphous nature and the Ca/P ratios became much closer to the value attributed to hydroxyapatite (1.67). The obtained results are very promising for the development of cancellous bone replacement materials and for pre-calcifying bone tissue engineering scaffolds.</p>