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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Gibson, Iain
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2020Natural and Synthetic Hydroxyapatitescitations
- 2020Ceramics, Glasses, and Glass-Ceramicscitations
- 2011Synthesis of Bioceramic Compositions
- 2008Optimisation of the aqueous precipitation synthesis of silicatesubstituted hydroxyapatite
- 2008Optimisation of the aqueous precipitation synthesis of silicate-substituted hydroxyapatite
- 2007Comparison of Carbonate Hydroxyapatite with and without Sodium Co-Substitutioncitations
- 2007Synthesis of Novel High Silicate-Substituted Hydroxyapatite by Co-Substitution Mechanismscitations
- 2006The uptake of titanium ions by hydroxyapatite particles-structural changes and possible mechanismscitations
- 2005In vivo assessment of hydroxyapatite and silicate-substituted hydroxyapatite granules using an ovine defect model
- 2003Calcium phosphate coatings obtained by Nd : YAG laser cladding: Physicochemical and biologic propertiescitations
- 2003Comparison of sintering and mechanical properties of hydroxyapatite and silicon-substituted hydroxyapatite
- 2002Ferroelasticity and hysteresis in LaCoO3 based perovskites
- 2002Porous glass reinforced hydroxyapatite materials produced with different organic additivescitations
- 2002Preparation and characterization of magnesium/carbonate co-substituted hydroxyapatitescitations
- 2002Characterisation of mono- and biphasic calcium phosphates granules
- 2002Effect of silicon substitution on the sintering and microstructure of hydroxyapatite
- 2001Production of calcium phosphate coatings on Ti6Al4V obtained by Nd : yttrium-aluminum-garnet laser cladding
- 2001Effect of chemical composition on hydrophobicity and zeta potential of plasma sprayed HA/CaO-P2O5 glass coatingscitations
- 2001Effect of powder characteristics on the sinterability of hydroxyapatite powderscitations
- 2001Calcining influence on the powder properties of hydroxyapatitecitations
- 2001Adsorption and release studies of sodium ampicillin from hydroxyapatite and glass-reinforced hydroxyapatite compositescitations
- 2001Particle size effects on apatite-wollastonite glass crystallisation
- 2000Influence of phase purity on the in vivo response to hydroxyapatite
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article
Adsorption and release studies of sodium ampicillin from hydroxyapatite and glass-reinforced hydroxyapatite composites
Abstract
<p>As a potential therapy for periodontitis, sodium ampicillin, a broad spectrum antibiotic, was adsorbed onto hydroxyapatite (HA) and glass-reinforced hydroxyaptite (GR-HA) composites, and was subsequently released in vitro. The sodium ampicillin, was adsorbed more on HA compared to the GR-IIA composites. X ray diffraction (XRD) and Rietveld analysis were used to identify and quantify the levels of HA and beta -tricalcium phosphate (beta -TCP) in the microstructure of the GR-HA composites, Lattice parameters changes were observed for the beta -TCP phase dependant on the amount of glass added. The release kinetics were shown to be divided into three stages, the first of which where a large amount of sodium ampicillin is released, followed by a slower release rate and then a final stage where the release amount approaches zero, until no more sodium ampicillin was present. X-ray photoelectron spectroscopy (XPS) studies were carried out in order to ensure that the entire antibiotic adsorbed onto the materials had been released. These kinetics studies have indicated the possibility of using these materials as possible carriers for drug delivery. (C) 2001 Elsevier Science Ltd. All rights reserved.</p>