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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Hernández, S.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (8/8 displayed)
- 2016Heterogeneous distribution of B-site cations in BaZrxTi1−xO3 epitaxial thin films grown on (0 0 1) SrTiO3 by pulsed laser depositioncitations
- 2015Observation of room temperature photoluminescence from asymmetric CuGaO2/ Zno/ZnMgo multiple quantum well structurescitations
- 2014Optimization of alternative distillation sequences for natural gas sweeteningcitations
- 2014New strategies in laser processing of TCOs for light management improvement in thin-film silicon solar cells
- 2012Characterization of water uptake by organic coatings used for the corrosion protection of steel as determined from capacitance measurements
- 2009Immunoassay for folic acid detection in vitamin-fortified milk based on electrochemical magneto sensorscitations
- 2007Bioaffinity platforms based on carbon-polymer biocomposites for electrochemical biosensingcitations
- 2007In situ DNA amplification with magnetic primers for the electrochemical detection of food pathogenscitations
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article
Bioaffinity platforms based on carbon-polymer biocomposites for electrochemical biosensing
Abstract
Rigid conducting biocomposites are interesting transducing materials for the construction of electrochemical immunosensors, genosensors and enzymosensors, particularly if the material is modified with universal affinity biomolecules. Examples of these 'universal affinity biocomposites' for electrochemical biosensing are reviewed, in which the common base material is a graphite-epoxy composite. The first approach relies on strept(avidin)-graphite-epoxy biocomposite transducer, as a universal immobilization platform whereon biotinylated biomolecules, such as DNAs, enzymes or antibodies can be captured by means of strept(avidin)-biotin reaction. The second approach is based on Protein A-graphite-epoxy biocomposite. Protein A is able to bind the Fc region of antibodies serving as generic affinity matrix for immuno-immobilization on the transducer. Biocomposite electrodes offer many potential advantages compared to more traditional electrodes based on a surface-modified conducting phase. The capability of integrating various materials into a single one is their main advantage, besides the improved electrochemical properties. These materials can just be prepared through 'dry chemistry' using procedures that can be easily transferred to mass fabrication of thick film devices. The different properties of these materials are discussed. Analytical response as well as other parameters such as the easiness in preparation, robustness, sensitivity, surface regeneration, costs, and transfer to mass production of these different approaches is also considered. © 2007 Elsevier B.V. All rights reserved.