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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Fabiano, S.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (9/9 displayed)
- 2023Improved Performance of Organic Thermoelectric Generators Through Interfacial Energeticscitations
- 2021Lactone backbone density in rigid electron-deficient semiconducting polymers enabling high n-type organic thermoelectric performancecitations
- 2021Lactone backbone density in rigid electron-deficient semiconducting polymers enabling high n-type organic thermoelectric performancecitations
- 2019Impact of Singly Occupied Molecular Orbital Energy on the n-Doping Efficiency of Benzimidazole-Derivativescitations
- 2018Air-Stable Benzimidazoline n-Type Dopants for Conductive Host Materials with Low Electron Affinities
- 2009Immunoassay for folic acid detection in vitamin-fortified milk based on electrochemical magneto sensorscitations
- 2007Bioaffinity platforms based on carbon-polymer biocomposites for electrochemical biosensingcitations
- 2005The EpiLink record linkage software: presentation and results of linkage test on cancer registry files.citations
- 2003Amperometric tyrosinase based biosensor using an electrogenerated polythiophene film as an entrapment support.citations
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article
Bioaffinity platforms based on carbon-polymer biocomposites for electrochemical biosensing
Abstract
Rigid conducting biocomposites are interesting transducing materials for the construction of electrochemical immunosensors, genosensors and enzymosensors, particularly if the material is modified with universal affinity biomolecules. Examples of these 'universal affinity biocomposites' for electrochemical biosensing are reviewed, in which the common base material is a graphite-epoxy composite. The first approach relies on strept(avidin)-graphite-epoxy biocomposite transducer, as a universal immobilization platform whereon biotinylated biomolecules, such as DNAs, enzymes or antibodies can be captured by means of strept(avidin)-biotin reaction. The second approach is based on Protein A-graphite-epoxy biocomposite. Protein A is able to bind the Fc region of antibodies serving as generic affinity matrix for immuno-immobilization on the transducer. Biocomposite electrodes offer many potential advantages compared to more traditional electrodes based on a surface-modified conducting phase. The capability of integrating various materials into a single one is their main advantage, besides the improved electrochemical properties. These materials can just be prepared through 'dry chemistry' using procedures that can be easily transferred to mass fabrication of thick film devices. The different properties of these materials are discussed. Analytical response as well as other parameters such as the easiness in preparation, robustness, sensitivity, surface regeneration, costs, and transfer to mass production of these different approaches is also considered. © 2007 Elsevier B.V. All rights reserved.