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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gonciarz, Weronika
University of Łódź
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (3/3 displayed)
- 20243D printing of dolutegravir-loaded polylactide filaments as a long-acting implantable system for HIV treatmentcitations
- 2024Improved antibacterial activity and biocompatibility of porphyrin functionalized metal decorated reduced graphene oxidecitations
- 2020Attenuated total reflectance fourier transform infrared spectroscopy (FTIR) and artificial neural networks applied to investigate quantitative changes of selected soluble biomarkers, correlated with H. pylori infection in children and presumable consequent delayed growthcitations
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article
Improved antibacterial activity and biocompatibility of porphyrin functionalized metal decorated reduced graphene oxide
Abstract
In this work, a facile, environmentally friendly, and simple synthesis approach for the preparation of porphyrinfunctionalized metal-decorated graphene through their unique and outstanding physicochemical properties isreported. In-vitro biocompatibility of the graphene-metal-porphyrin nanocomposites was assessed in the L929cell line via the MTT reduction method. Further, the antibacterial activity of the graphene-metal-porphyrinnanocomposite was investigated and compared with bare graphene-porphyrin against gram-positive S. aureus(ATCC 6538) and gram-negative E. coli (ATTC 25922) bacteria using an MTT assay. As a result of the investigation, it is found that graphene-Ag-porphyrin exhibited excellent biocompatibility and antibacterial properties.The porphyrin functionalized with different metal-loading nanocomposites and their structural, morphologiesalong with linear optical properties were investigated by Raman, FTIR, XPS, FESEM, TEM, UV–vis, and PL. Theenhanced biological properties of the composites arise mainly due to tailoring the proportion of covalent andnon-covalent containing groups in the graphene layer, and the graphene-Ag-porphyrin scaffolds exhibit excellentbio-safety for further clinical translational use.