| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Meenan, Brian
in Cooperation with on an Cooperation-Score of 37%
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Publications (7/7 displayed)
- 2023Nanotopography of Polystyrene/Poly(methyl methacrylate) for the Promotion of Patient Specific Von Willebrand Factor Entrapment and Platelet Adhesion in a Whole Blood Microfluidic Assay
- 20223D Fabrication and Characterisation of Electrically Receptive PCL-Graphene Scaffolds for Bioengineered In Vitro Tissue Modelscitations
- 2022Biocompatible Nanocomposite Coatings Deposited via Layer-by-Layer Assembly for the Mechanical Reinforcement of Highly Porous Interconnected Tissue-Engineered Scaffoldscitations
- 2022Nanoindentation and nano-scratching of hydroxyapatite coatings for resorbable magnesium alloy bone implant applicationscitations
- 2022Shear testing and failure modelling of calcium phosphate coated AZ31 magnesium alloys for orthopaedic applicationscitations
- 2021Effects of strontium-substitution in sputter deposited calcium phosphate coatings on the rate of corrosion of magnesium alloyscitations
- 2017Entrapment of Autologous von Willebrand Factor on Polystyrene/Poly(methyl methacrylate) Demixed Surfacescitations
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article
Effects of strontium-substitution in sputter deposited calcium phosphate coatings on the rate of corrosion of magnesium alloys
Abstract
Magnesium (Mg) alloys have significant potential for use as bioresorbable orthopaedic implant devices due to their controllable mechanical properties and an ability to promote new bone growth. However, difficulty lies with controlling the rate of corrosion in physiological conditions to ensure the load-bearing capability of the device is maintained for the required period of time, specifically until an adequate quantity of new bone tissue is formed. In this work, RF magnetron sputtering has been used to create calcium phosphate (CaP) and strontium-substituted calcium phosphate (SrCaP) thin film coatings on two Mg alloy systems (denoted WJK and ZEWX) that have been formulated for the fabrication of orthopaedic fracture fixation devices. A 14-day static-dynamic immersion study in simulated body fluid (SBF), shows that uncoated WJK substrates had a corrosion rate of 4.04 ± 0.15 millimetres per year (mmpy), which was reduced to 3.22 ± 0.17 mmpy with the application of a CaP coating, and to 2.92 ± 0.05 mmpy with a SrCaP coating. Uncoated ZEWX substrates had a corrosion rate of 3.36 ± 0.05 mmpy which was reduced to 2.98 ± 0.19 mmpy and 2.79 ± 0.03 mmpy, for CaP and SrCaP coatings, respectively. Whereas the sputter-deposited CaP and SrCaP coatings completely dissolve in SBF over the period of immersion, their presence at the outset significantly decreases the corrosion rate of both Mg alloys, as compared to the values for the uncoated substrates. Successful incorporation of Sr within the coating offers the potential for improved bioactivity with respect to directing the bone cell response to create new tissue.