| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Hashim, Uda
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2023Dielectric Properties and Microwave Absorbing Properties of Silicon Carbide Nanoparticles and Silicon Carbide Nanowhiskers
- 2023Formation of polypropylene nanocomposite joint using silicon carbide nanowhiskers as novel susceptor for microwave weldingcitations
- 2019Fabrication of gold nanorod–zinc oxide nanocomposite on gap-fingered integrated interdigitated aluminum electrodes and their response to electrolytescitations
- 2017Synthesis of silicon carbide nanowhiskers by microwave heating: effect of heating durationcitations
- 2017Substrate-gate coupling in ZnO-FET biosensor for cardiac troponin I detectioncitations
- 2016Novel synthesis of silicon carbide nanotubes by microwave heating of blended silicon dioxide and multi-walled carbon nanotubes: The effect of the heating temperaturecitations
- 2016Interdigitated Electrodes integrated with zinc oxide nanoparticles for Cardiac Troponin I biomarker detectioncitations
- 2015Ab initio method of optical investigations of CdS1−xTex alloys under quantum dots diameter effectcitations
- 2015Real-time detection by properties of tin dioxide for formaldehyde gas sensorcitations
- 2015Structural, optical and electrical properties of Cu2Zn1źxCdxSnS4 quinternary alloys nanostructures deposited on porous siliconcitations
- 2015Deposition and characterization of ZnO thin film for FET with back gate biasing-based biosensors applicationcitations
- 2014Glass etching for cost-effective microchannels fabricationcitations
- 2014Selective growth of ZnO nanorods on microgap electrodes and their applications in UV sensors
- 2012Sol-gel Synthesis of TiO 2 Thin Films from In-house Nano-TiO 2 Powder
- 2008Silicon nitride gate ISFET fabrication based on four mask layers using standard MOSFET technologycitations
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article
Substrate-gate coupling in ZnO-FET biosensor for cardiac troponin I detection
Abstract
urrently, field-effect transistor (FET)-based biosensors have been implemented in several portable sensors with the ultimate application in point-of-care testing (POCT). In this paper, we have designed substrate-gate coupling in FET-based biosensor for the detection of cardiac troponin I (cTnI) biomarker. In the device structure, zinc oxide nanoparticles (ZnO-NPs) thin film were deposited through sol-gel and spin coating techniques on the channel. The p-type silicon was used as a substrate, while ZnO is an n-type nanomaterial, thus creates p - n- p junction between source, channel, and drain. The deposited thin films exhibited hexagonal wurtzite phase of ZnO, suitable for biomolecular interaction as revealed in X-ray diffraction (XRD) analysis. The surface of the thin film was then functionalized with 3-aminopropyltriethoxysilane (APTES), followed by glutaraldehyde (GA) as a bi-functional linker to immobilize the cTnI monoclonal antibody (MAb-cTnI) as bio-receptor for capturing cTnI biomarker and proven by the Fourier transform-infrared (FT-IR) spectra. Lastly, we demonstrated a new strategy, the integration of FET-based biosensors with substrate-gate showed differences between before (immobilization) and after cTnI target biomarker interaction by significant changes in drain current (I D ) and change of threshold voltage (V T ), which improved the sensitive detection, with the limit of detection down to 3.24 pg/ml.