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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gu, J.
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Publications (6/6 displayed)
- 2023In Situ Study of the Degradation Behaviour Under Load of Mg1.8Y0.6Zn(1Ag) Using Synchrotron Tomographycitations
- 2023Nano-carrier for gene delivery and bioimaging based on pentaetheylenehexamine modified carbon dotscitations
- 2022Chrysanthemum species used as food and medicine: Understanding quality differences on the global marketcitations
- 2014Comparison of Shearography to Scanning Laser Vibrometry as Methods for Local Stiffness Identification of Beamscitations
- 2012Experimental and numerical polar scans of several anisotropic materials using pulsed and harmonic ultrasonic beams
- 2011P1-01-12: Mesoporous Silicon Particles for the Presentation of Tumor Antigens and Adjuvant for Anti-Cancer Immunity.
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article
Chrysanthemum species used as food and medicine: Understanding quality differences on the global market
Abstract
BackgroundChrysanthemum flowers [Ch. x morifolium (Ramat.) Hemsl. and Ch. indicum L.] are a globally used and pharmacologically interesting botanical drug, however, with variable product quality.ObjectiveWe aim at understanding the chemical variability of primary material available commercially based on different origins and associated quality problems like contamination with heavy metals. This needs to be assessed in the context of the current regulations for this botanical drug and associated problems.Material and Methods15 C. indicum L. and 50 C. x morifolium (Ramat.) Hemsl., including a range of geographical cultivars recognized in China, samples from the USA, Europe and China were analyzed using High Performance Thin Layer Chromatography (HPTLC) to compare their general chemical profile. Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) was used to quantify heavy metal contamination.ResultsThe: HPTLC fingerprints of C. indicum samples are clearly distinguishable from C. x morifolium. Fingerprints of samples from the same cultivars collected from markets in different countries (USA and China) show different patterns. Large variance of fingerprints within each cultivar group was observed. The heavy metal analysis showed excessive amounts of some harmful heavy metal in some commercial products with excessive cadmium being the most frequent problem.ConclusionsThe Chinese medicinal cultivars vary. Differences between samples sourced from the USA and China might be ascribable to geographical factors (e.g. soil composition), degradation during transport/storage or adulteration, but geographical differences should also be taken into account. Importantly, a much more detailed definition of the drug are needed for better quality control. In addition, with continuous contamination problem observed, a more widespread regulation is an essential requirement for better quality.