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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Kumar, Mukesh
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (11/11 displayed)
- 2024Unveiling the Impact of Processing Parameters on Microstructure and Mechanical Properties of Hybrid Composites Developed via Friction Stir Processingcitations
- 2024Impact response of filament-wound structure with polymeric liner: Experimental and numerical investigation (Part-A)citations
- 2024In situ ex-solution of CoFeRu solid solution nanoparticles from non-stoichiometric (La$_{0.8}$Sr$_{0.2}$)$_{0.9}$Co$_{0.1}$Fe$_{0.8}$Ru$_{0.1}$O$_{3−δ}$ perovskite for hydrogen gas sensor
- 2023Improving Biocompatibility for Next Generation of Metallic Implants.citations
- 2023Novel technique of vibration minimization during hard machiningcitations
- 2023Efficient Hotel Review Rating Prediction using Ensemble Learningcitations
- 2023Parametric optimization and ranking analysis of basalt fiber–marble dust particulates–polyamide 66 polymer composites under dry sliding wear investigationcitations
- 2022Microstructure, Mechanical, and Nanotribological Properties of Ni, Ni-TiN, and Ni90Cu10-TiN Films Processed by Reactive Magnetron Cosputteringcitations
- 2019Effect of Artificial Aging Temperature on Mechanical Properties of 6061 Aluminum Alloy
- 2016Cu–Zn disorder and band gap fluctuations in Cu2ZnSn(S,Se)4 : Theoretical and experimental investigationscitations
- 2012Band Gap and Conductivity Measurement of TiO<sub>2</sub> Thin Films Deposited by Sol-Gel Spin Coating Methodcitations
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article
Improving Biocompatibility for Next Generation of Metallic Implants.
Abstract
The increasing need for joint replacement surgeries, musculoskeletal repairs, and orthodontics worldwide prompts emerging technologies to evolve with healthcare's changing landscape. Metallic orthopaedic materials have a shared application history with the aerospace industry, making them only partly efficient in the biomedical domain. However, suitability of metallic materials in bone tissue replacements and regenerative therapies remains unchallenged due to their superior mechanical properties, eventhough they are not perfectly biocompatible. Therefore, exploring ways to improve biocompatibility is the most critical step toward designing the next generation of metallic biomaterials. This review discusses methods of improving biocompatibility of metals used in biomedical devices using surface modification, bulk modification, and incorporation of biologics. Our investigation spans multiple length scales, from bulk metals to the effect of microporosities, surface nanoarchitecture, and biomolecules such as DNA incorporation for enhanced biological response in metallic materials. We examine recent technologies such as 3D printing in alloy design and storing surface charge on nanoarchitecture surfaces, metal-on-metal, and ceramic-on-metal coatings to present a coherent and comprehensive understanding of the subject. Finally, we consider the advantages and challenges of metallic biomaterials and identify future directions.