Materials Map

Discover the materials research landscape. Find experts, partners, networks.

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The Materials Map is an open tool for improving networking and interdisciplinary exchange within materials research. It enables cross-database search for cooperation and network partners and discovering of the research landscape.

The dashboard provides detailed information about the selected scientist, e.g. publications. The dashboard can be filtered and shows the relationship to co-authors in different diagrams. In addition, a link is provided to find contact information.

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The Materials Map is still under development. In its current state, it is only based on one single data source and, thus, incomplete and contains duplicates. We are working on incorporating new open data sources like ORCID to improve the quality and the timeliness of our data. We will update Materials Map as soon as possible and kindly ask for your patience.

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in Cooperation with on an Cooperation-Score of 37%

Topics

Publications (2/2 displayed)

  • 2013Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat25citations
  • 2013H63D polymorphism in HFE is not associated with amyotrophic lateral sclerosis24citations

Places of action

Chart of shared publication
Lewis, Cathryn
1 / 5 shared
Shaw, Pamela J.
2 / 2 shared
Jones, Ashley R.
1 / 1 shared
Woollacott, Ione
1 / 1 shared
Cooper-Knock, Johnathan
1 / 1 shared
Smith, Bradley
2 / 3 shared
Buchman, Vladimir
1 / 1 shared
Sproviero, William
1 / 1 shared
Shaw, Christopher
2 / 4 shared
Mcguffin, Peter
1 / 4 shared
Ellis, Catherine M.
1 / 1 shared
Morrison, Karen E.
2 / 2 shared
Shatunov, Aleksey
2 / 2 shared
Scott, Kirsten M.
1 / 1 shared
Balendra, Rubika
1 / 1 shared
Abel, Olubunmi
1 / 1 shared
Powell, John
1 / 7 shared
Farmer, Anne
1 / 1 shared
Leigh, P. Nigel
1 / 1 shared
Chart of publication period
2013

Co-Authors (by relevance)

  • Lewis, Cathryn
  • Shaw, Pamela J.
  • Jones, Ashley R.
  • Woollacott, Ione
  • Cooper-Knock, Johnathan
  • Smith, Bradley
  • Buchman, Vladimir
  • Sproviero, William
  • Shaw, Christopher
  • Mcguffin, Peter
  • Ellis, Catherine M.
  • Morrison, Karen E.
  • Shatunov, Aleksey
  • Scott, Kirsten M.
  • Balendra, Rubika
  • Abel, Olubunmi
  • Powell, John
  • Farmer, Anne
  • Leigh, P. Nigel
OrganizationsLocationPeople

article

H63D polymorphism in HFE is not associated with amyotrophic lateral sclerosis

  • Hardiman, Orla
  • Weber, Markus
  • Berg, Leonard H. Van Den
  • Kooi, Anneke J. Van Der
  • Diekstra, Frank P.
  • Ludolph, Albert C.
  • Waibel, Stefan
  • Morrison, Karen E.
  • Mclaughlin, Russell
  • Seelen, Meinie
  • Vught, Paul W. J. Van
  • Czell, David
  • Shaw, Pamela J.
  • Robberecht, Wim
  • Visser, Marianne De
  • Al-Chalabi, Ammar
  • Rheenen, Wouter Van
  • Veldink, Jan H.
  • Schelhaas, H. Jurgen
  • Smith, Bradley
  • Andersen, Peter M.
  • Shaw, Christopher
  • Damme, Philip Van
  • Kenna, Kevin
  • Shatunov, Aleksey
  • Doormaal, Perry T. C. Van
  • Es, Michael A. Van
Abstract

<p>The H63D polymorphism in HFE has frequently been associated with susceptibility to amyotrophic lateral sclerosis (ALS). Regarding the role of HFE in iron homeostasis, iron accumulation is considered an important process in ALS. Furthermore, novel therapeutic strategies are being developed targeting this process. Evidence for this genetic association is, however, limited to several small studies. For this reason we studied the H63D polymorphism in a large European cohort including 3962 ALS patients and 5072 control subjects from 7 countries. After meta-analysis of previous studies and current findings we conclude that the H63D polymorphism in HFE is not associated with susceptibility to ALS, age at disease onset, or survival.</p>

Topics
  • impedance spectroscopy
  • iron
  • susceptibility