| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Kellomäki, Minna
Tampere University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (31/31 displayed)
- 2024A comprehensive study on rheological properties of photocrosslinkable gallol-metal complexed hyaluronic acid-based biomaterial inkscitations
- 2023Comprehensive characterisation of the compressive behaviour of hydrogels using a new modelling procedure and redefining compression testingcitations
- 2023Interpretable machine learning methods for monitoring polymer degradation in extrusion of polylactic acidcitations
- 2023Hydrolytic degradation of polylactide/polybutylene succinate blends with bioactive glasscitations
- 2023Chemical interactions in composites of gellan gum and bioactive glass: self-crosslinking and in vitro dissolutioncitations
- 2022Fractal-like Hierarchical CuO Nano/Microstructures for Large-Surface-to-Volume-Ratio Dip Catalystscitations
- 2022Injectable and self-healing biobased composite hydrogels as future anticancer therapeutic biomaterialscitations
- 2021Comprehensive characterisation of the compressive behaviour of hydrogels using a new modelling procedure and redefining compression testingcitations
- 2021Impact of glass composition on hydrolytic degradation of polylactide/bioactive glass compositescitations
- 2021In vitro degradation testing of hydrogels – concept and case study of gellan gum degradation in water
- 2020Evaluation of scaffold microstructure and comparison of cell seeding methods using micro-computed tomography-based toolscitations
- 2020Materials and Orthopedic Applications for Bioresorbable Inductively Coupled Resonance Sensorscitations
- 2020A tube-source X-ray microtomography approach for quantitative 3D microscopy of optically challenging cell-cultured samplescitations
- 2019Hydrolysis and drug release from poly(ethylene glycol)-modified lactone polymers with open porositycitations
- 2019Gas-foamed poly(lactide-co-glycolide) and poly(lactide-co-glycolide) with bioactive glass fibres demonstrate insufficient bone repair in lapine osteochondral defectscitations
- 2019Characterization of the microstructure of hydrazone crosslinked polysaccharide-based hydrogels through rheological and diffusion studiescitations
- 2019Characterization of the microstructure of hydrazone crosslinked polysaccharide-based hydrogels through rheological and diffusion studiescitations
- 2018Knitted 3D Scaffolds of Polybutylene Succinate Support Human Mesenchymal Stem Cell Growth and Osteogenesiscitations
- 2018Cell response to round and star-shaped polylactide fibers
- 2018Bioresorbable Conductive Wire with Minimal Metal Contentcitations
- 2017In vitro degradation of borosilicate bioactive glass and poly(L-lactide-co-ε-caprolactone) composite scaffoldscitations
- 2016Piezoelectric sensitivity of a layered film of chitosan and cellulose nanocrystalscitations
- 2016Inductively coupled passive resonance sensor for monitoring biodegradable polymers in vitrocitations
- 2016X-ray microtomography of collagen and polylactide samples in liquidscitations
- 2014Direct laser writing of synthetic poly(amino acid) hydrogels and poly(ethylene glycol) diacrylates by two-photon polymerizationcitations
- 2013Novel polypyrrole-coated polylactide scaffolds enhance adipose stem cell proliferation and early osteogenic differentiationcitations
- 2013An in vitro study of composites of poly(L-lactide-co-e-caprolactone), ß-tricalcium phosphate and ciprofloxacin intended for local treatment of osteomyelitiscitations
- 2012Processing and sustained in vitro release of rifampicin containing composites to enhance the treatment of osteomyelitiscitations
- 2011Knitted polylactide 96/4 L/D structures and scaffolds for tissue engineeringcitations
- 2011Investigation of the optimal processing parameters for picosecond laser-induced microfabrication of a polymer-ceramic hybrid materialcitations
- 2008Nano-, Pico- and femtosecond laser machining of bioabsorbable polymers and biomedical composites
Places of action
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article
Hydrolytic degradation of polylactide/polybutylene succinate blends with bioactive glass
Abstract
Polylactides (PLAs) have been vastly studied for biomedical engineering applications, but their rigidness limits their use. Blending them with more flexible polymers, such as polybutylene succinate (PBSu), results in softer materials, expanding the range of possible applications. However, the biopolymers lack bioactivity, which can be overcome by adding bioactive glass. Combining the inorganic phase with the organic phase (especially with blends) results in a complex material. Therefore, understanding the hydrolytic degradation of each component is crucial. In this context, we report on processing polylactide and polybutylene succinate (PLA/PBSu) blends and their composites (30 wt% of bioactive glass 13-93, BaG). The impact of blending and compounding with BaG on the final product’s molecular weight and mechanical properties and the BaG dispersion in the polymer matrices was assessed. In addition, in vitro degradation in PBS was studied. While the degradation of the polymer was assessed by GPC, the BaG dissolution was quantified by ICP-OES. Blending decreased the initial mechanical properties and molecular weight, and compounding with BaG further decreased the initial mechanical properties. During the immersion in PBS, blending accelerated the loss of mechanical properties and molecular weight, while BaG accelerated the degradation of PLA-containing materials but had little effect on PBSu. Blending and compounding with BaG enabled us to produce materials with a wide range of mechanical properties: bending strength of 34–125 MPa, shear strength of 22–47 MPa and bending modulus of 1.1–3.9 GPa. The selection of tailorable properties of these polymer/BaG composites enables their application for tissue engineering of bone to soft tissue. ; Peer reviewed