| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Pou, Juan
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (11/11 displayed)
- 2024Influence of CO2 laser surface treatment of basalt fibers on the mechanical properties of epoxy/basalt compositescitations
- 2023Cobalt containing glass fibres and their synergistic effect on the HIF-1 pathway for wound healing applicationscitations
- 2022Laser-deposited beta type Ti-42Nb alloy with anisotropic mechanical properties for pioneering biomedical implants with a very low elastic moduluscitations
- 2022Palladium nanoparticles synthesized by laser ablation in liquids for antimicrobial applicationscitations
- 20223D printing with star-shaped strands: A new approach to enhance in vivo bone regenerationcitations
- 2021In-situ laser directed energy deposition of biomedical Ti-Nb and Ti-Zr-Nb alloys from elemental powderscitations
- 2021In-Situ Laser Directed Energy Deposition of Biomedical Ti-Nb and Ti-Zr-Nb Alloys from Elemental Powderscitations
- 20213D printing non-cylindrical strands: Morphological and structural implicationscitations
- 2021Hyaluronic acid hydrogels reinforced with laser spun bioactive glass micro- and nanofibres doped with lithiumcitations
- 2019Synthesis and Deposition of Ag Nanoparticles by Combining Laser Ablation and Electrophoretic Deposition Techniquescitations
- 2013Nanocomposites of silver nanoparticles embedded in glass nanofibres obtained by laser spinningcitations
Places of action
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article
Hyaluronic acid hydrogels reinforced with laser spun bioactive glass micro- and nanofibres doped with lithium
Abstract
The repair of articular cartilage lesions in weight-bearing joints remains as a significant challenge due to the low regenerative capacity of this tissue. Hydrogels are candidates to repair lesions as they have similar properties to cartilage extracellular matrix but they are unable to meet the mechanical and biological requirements for a successful outcome. Here, we reinforce hyaluronic acid (HA) hydrogels with 13-93-lithium bioactive glass micro- and nanofibres produced by laser spinning. The glass fibres are a reinforcement filler and a platform for the delivery of therapeutic lithium-ions. The elastic modulus of the composites is more than three times higher than in HA hydrogels. Modelling of the reinforcement corroborates the experimental results. ATDC5 chondrogenic cells seeded on the composites are viable and more proliferation occurs on the hydrogels containing fibres than in HA hydrogels alone. Furthermore, the chondrogenic behavior on HA constructs with fibres containing lithium is more marked than in hydrogels with no-lithium fibres.