| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Schubert, Dirk W.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (20/20 displayed)
- 2025Ti3C2Tx‐UHMWPE Nanocomposites—Towards an Enhanced Wear‐Resistance of Biomedical Implantscitations
- 2024Chemical Synthesis of Atactic Poly-3-hydroxybutyrate (a-P3HB) by Self-Polycondensation: Catalyst Screening and Characterizationcitations
- 2024Genipin-Cross-Linked Silk Fibroin/Alginate Dialdehyde Hydrogel with Tunable Gelation Kinetics, Degradability, and Mechanical Properties: A Potential Candidate for Tissue Regenerationcitations
- 2023Progress on Electrospun Composite Fibers Incorporating Bioactive Glass: An Overviewcitations
- 20233D-Printed Multifunctional Hydrogels with Phytotherapeutic Properties: Development of Essential Oil-Incorporated ALG-XAN Hydrogels for Wound Healing Applicationscitations
- 2023Pre‐Crosslinking with Hydrogel Microparticles Enhances the Printability of Alginate‐Based Inkscitations
- 2023Model to Predict Polymer Fibre Diameter during Melt Spinningcitations
- 2022Stress relaxation amplitude of hydrogels determines migration, proliferation, and morphology of cells in 3-D culturecitations
- 2022Improved 3D Printing and Cell Biology Characterization of Inorganic-Filler Containing Alginate-Based Composites for Bone Regeneration: Particle Shape and Effective Surface Area Are the Dominant Factors for Printing Performancecitations
- 2022Hierarchical Slice Patterns Inhibit Crack Propagation in Brittle Sheetscitations
- 2021Hemp Fiber Reinforced Red Mud/Fly Ash Geopolymer Composite Materials: Effect of Fiber Content on Mechanical Strengthcitations
- 2021An organic-inorganic hybrid scaffold with honeycomb-like structures enabled by one-step self-assembly-driven electrospinningcitations
- 2021Molecular changes induced in melanoma by cell culturing in 3D alginate hydrogelscitations
- 2021Revealing Electrical and Mechanical Performances of Highly Oriented Electrospun Conductive Nanofibers of Biopolymers with Tunable Diametercitations
- 2020Comparison of hydrogels for the development of well-defined 3d cancer models of breast cancer and melanomacitations
- 2020Preparation and Characterization of Electrospun Blend Fibrous Polyethylene Oxide:Polycaprolactone Scaffolds to Promote Cartilage Regenerationcitations
- 2020On the Determination of the Enthalpy of Fusion of α‐Crystalline Isotactic Polypropylene Using Differential Scanning Calorimetry, X‐Ray Diffraction, and Fourier‐Transform Infrared Spectroscopy: An Old Story Revisitedcitations
- 2020Cell-laden alginate dialdehyde–gelatin hydrogels formed in 3D printed sacrificial gelcitations
- 2019Polymer-Functionalised Nanograins of Mg-Doped Amorphous Calcium Carbonate via a Flow-Chemistry Approachcitations
- 2019Curcumin-Containing Orthopedic Implant Coatings Deposited on Poly-Ether-Ether-Ketone/Bioactive Glass/Hexagonal Boron Nitride Layers by Electrophoretic Depositioncitations
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article
An organic-inorganic hybrid scaffold with honeycomb-like structures enabled by one-step self-assembly-driven electrospinning
Abstract
Electrospun organic/inorganic hybrid scaffolds have been appealing in tissue regeneration owing to the integrated physiochemical and biological performances. However, the conventional electrospun scaffolds with non-woven structures usually failed to enable deep cell infiltration due to the densely stacked layers among the fibers. Herein, through self-assembly-driven electrospinning, a polyhydroxybutyrate/poly(ε-caprolactone)/58S sol-gel bioactive glass (PHB/PCL/58S) hybrid scaffold with honeycomb-like structures was prepared by manipulating the solution composition and concentration during a one-step electrospinning process. Here, the mechanisms enabling the formation of self-assembled honeycomb-like structures were investigated through comparative studies using Fourier-transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) between PHB/PCL/58S and PHB/PCL/sol-gel silica systems. The obtained honeycomb-like structure was built up from nanofibers with an average diameter of 370 nm and showed a bimodal distribution of pores: large polygonal pores up to hundreds of micrometers within the honeycomb-cells and irregular pores among the nanofibers ranging around few micrometers. The cell-materials interactions were further studied by culturing MG-63 osteoblast-like cells for 7 days. Cell viability, cell morphology and cell infiltration were comparatively investigated as well. While cells merely proliferated on the surface of non-woven structures, MG-63 cells showed extensive proliferation and deep infiltration up to 100~200 μm into the honeycomb-like structure. Moreover, the cellular spatial organization was readily regulated by the honeycomb-like pattern as well. Overall, the newly obtained hybrid scaffold may integrate the enhanced osteogenicity originating from the bioactive components, and the improved cell-material interactions brought by the honeycomb-like structure, making the new scaffold a promising candidate for tissue regeneration.