| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
| |
| Motta, Antonella |
| |
| Aletan, Dirar |
| |
| Mohamed, Tarek |
| |
| Ertürk, Emre |
| |
| Taccardi, Nicola |
| |
| Kononenko, Denys |
| |
| Petrov, R. H. | Madrid |
|
| Alshaaer, Mazen | Brussels |
|
| Bih, L. |
| |
| Casati, R. |
| |
| Muller, Hermance |
| |
| Kočí, Jan | Prague |
|
| Šuljagić, Marija |
| |
| Kalteremidou, Kalliopi-Artemi | Brussels |
|
| Azam, Siraj |
| |
| Ospanova, Alyiya |
| |
| Blanpain, Bart |
| |
| Ali, M. A. |
| |
| Popa, V. |
| |
| Rančić, M. |
| |
| Ollier, Nadège |
| |
| Azevedo, Nuno Monteiro |
| |
| Landes, Michael |
| |
| Rignanese, Gian-Marco |
|
Dolatshahi-Pirouz, Alireza
Technical University of Denmark
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (19/19 displayed)
- 2024Engineering Photo-Cross-Linkable MXene-Based Hydrogels:Durable Conductive Biomaterials for Electroactive Tissues and Interfacescitations
- 2024Engineering Photo-Cross-Linkable MXene-Based Hydrogels: Durable Conductive Biomaterials for Electroactive Tissues and Interfacescitations
- 2023Multi-leveled Nanosilicate Implants Can Facilitate Near-Perfect Bone Healingcitations
- 2023Composite Graded Melt Electrowritten Scaffolds for Regeneration of the Periodontal Ligament-to-Bone Interfacecitations
- 2022Bioinspired gelatin/bioceramic composites loaded with bone morphogenetic protein-2 (BMP-2) promote osteoporotic bone repaircitations
- 2021Design and construction of a novel measurement device for mechanical characterization of hydrogelscitations
- 2021Design and construction of a novel measurement device for mechanical characterization of hydrogels:A case studycitations
- 2021Combinatorial fluorapatite-based scaffolds substituted with strontium, magnesium and silicon ions for mending bone defectscitations
- 2021Rheological characterization of 3D printable geopolymerscitations
- 20193D-printed bioactive scaffolds from nanosilicates and PEOT/PBT for bone tissue engineeringcitations
- 20193D-printed bioactive scaffolds from nanosilicates and PEOT/PBT for bone tissue engineeringcitations
- 2019Self-Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?citations
- 2019Silica nanoparticle surface chemistry: An important trait affecting cellular biocompatibility in two and three dimensional culture systemscitations
- 2019Combating Microbial Contamination with Robust Polymeric Nanofibers: Elemental Effect on the Mussel-Inspired Cross-Linking of Electrospun Gelatincitations
- 2017Nanoreinforced Hydrogels for Tissue Engineering: Biomaterials that are Compatible with Load-Bearing and Electroactive Tissuescitations
- 2017Nanoreinforced hydrogels for tissue engineering:Biomaterials that are compatible with load-bearing and electroactive tissuescitations
- 2016Injectable shear-thinning nanoengineered hydrogels for stem cell deliverycitations
- 2011Growth characteristics of inclined columns produced by Glancing Angle Deposition (GLAD) and colloidal lithographycitations
- 2010Synthesis of functional nanomaterials via colloidal mask templating and glancing angle deposition (GLAD)”
Places of action
| Organizations | Location | People |
|---|
article
Combinatorial fluorapatite-based scaffolds substituted with strontium, magnesium and silicon ions for mending bone defects
Abstract
In bone tissue engineering, ionic doping using bone-related minerals such as magnesium (Mg) or strontium (Sr) is a promising strategy to make up for the inherent disadvantages (low solubility) of various apatite-based materials such as Fluorapatite (FAp) and Hydroxyapatite (HA). Therefore, number of studies in recent years have tried to address the lack-of-methodology to improve the properties of bioceramics in the field. Even though, the outcome of the studies has shown some promises, the influence of doped elements on the structures and properties of in vitro and in vivo mineralized FAp has not been investigated in detail so far, and thus, it is still an open question mark in the field. In this work, strontium modified fluorapatite (Sr-FAp), magnesium and silica modified fluorapatite (Mg-SiFAp) nanopowders were synthesized using a mechanical alloying methodology. Results showed that the doped elements could decrease the crystallinity of FAp (56%) to less than 45% and 39% for Sr-FAp and Mg-SiFAp, respectively. Moreover, in vitro studies revealed that Sr-FAp significantly enhanced osteogenic differentiation of hMSCs, after 21 days of culture, compared to Mg-SiFAp at both osteogenic and normal media. Then, in vivo bone formation in a defect of rat femur filled with a Sr-FAp and Mg-SiFAp compared to empty defect was investigated. Histological analysis revealed an increase in bone formation three weeks after implanting Sr-FAp compared to Mg-SiFAp and the empty defect. These results suggest that compared to magnesium and silica, strontium ion significantly promotes bone formation in fluorapatite making it appropriate for filling bone defects.