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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Mota, Carlos
European Commission
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (27/27 displayed)
- 2024Upcycling Fishing Net Waste and Metal Oxide from Electroplating Waste into Alga Cultivation Structures with Antibacterial Properties
- 2023Blast fragment impact of angle-ply composite structures for buildings wall protectioncitations
- 2023Chitin nanofibrils modulate mechanical response in tympanic membrane replacementscitations
- 2023Matrix metalloproteinase degradable, in situ photocrosslinked nanocomposite bioinks for bioprinting applicationscitations
- 2022Advanced Coatings of Polyureas for Building Blast Protection: Physical, Chemical, Thermal and Mechanical Characterizationcitations
- 2021Shaping and properties of thermoplastic scaffolds in tissue regeneration: The effect of thermal history on polymer crystallization, surface characteristics and cell fatecitations
- 2021Additive manufactured scaffolds for bone tissue engineering: Physical characterization of thermoplastic composites with functional fillerscitations
- 2021Bioprinting Via a Dual-Gel Bioink Based on Poly(Vinyl Alcohol) and Solubilized Extracellular Matrix towards Cartilage Engineeringcitations
- 2021Additive Manufactured Scaffolds for Bone Tissue Engineering: Physical Characterization of Thermoplastic Composites with Functional Fillerscitations
- 2021Controllable four axis extrusion-based additive manufacturing system for the fabrication of tubular scaffolds with tailorable mechanical propertiescitations
- 2021Chitin Nanofibril Application in Tympanic Membrane Scaffolds to Modulate Inflammatory and Immune Responsecitations
- 2021Study of the Filtration Performance of Multilayer and Multiscale Fibrous Structurescitations
- 2019Conception and characterization of different properties from a composite thermoformable with polymeric matrix and cellulosic fibres
- 2018Characterization of recycled carbon fibers reinforcing thermoplastic polymers
- 2018Influence of carbon nanotubes in the performance of a composite materials for ballistic helmets
- 2017Additive manufacturing of poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] scaffolds for engineered bone developmentcitations
- 2016Surface energy and stiffness discrete gradients in additive manufactured scaffolds for osteochondral regenerationcitations
- 2016Surface energy and stiffness discrete gradients in additive manufactured scaffolds for osteochondral regenerationcitations
- 2016Pseudo-ductile Braided Composite Rods (BCRs) produced by braidtrusion
- 2015Mechanical characterization of bio-epoxy ecocomposites reinforced with fibrous structures based on natural fibers
- 2015Processing and characterization of plates made from granulate of waste electrical cables
- 2015Mechanical properties of polypropylene/natural fiber composites: comparison with glass fiber
- 2014Estudo da adesão entre os materiais que constituem uma estrutura compósitas multicamada
- 2014Desenvolvimento e caracterização de varões compósitos híbridos para reforço de betão
- 2014Desenvolvimento de painéis compósitos multicamada com propriedades de resistência ao fogo
- 2014Development of multi-layer fibrous composites for fire resistant and sound insulating doors
- 2014Interfacing polymeric scaffolds with primary pancreatic ductal adenocarcinoma cells to develop 3D cancer modelscitations
Places of action
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article
Controllable four axis extrusion-based additive manufacturing system for the fabrication of tubular scaffolds with tailorable mechanical properties
Abstract
Many tubular tissues such as blood vessels and trachea can suffer long-segmental defects through trauma and disease. With current limitations in the use of autologous grafts, the need for a synthetic substitute is of continuous interest as possible alternatives. Fabrication of these tubular organs is commonly done with techniques such as electrospinning and melt electrowriting using a rotational collector. Current additive manufacturing (AM) systems do not commonly implement the use of a rotational axis, which limits their application for the fabrication of tubular scaffolds. In this study, a four axis extrusion-based AM system similar to fused deposition modeling (FDM) has been developed to create tubular hollow scaffolds. A rectangular and a diamond pore design were further investigated for mechanical characterization, as a standard and a biomimicry pore geometry respectively. We demonstrated that in the radial compression mode the diamond pore design had a higher Young's modulus (19,8 +/- 0,7 MPa compared to 2,8 +/- 0,5 MPa), while in the longitudinal tensile mode the rectangular pore design had a higher Young's modulus (5,8 +/- 0,2 MPa compared to 0,1 +/- 0,01 MPa). Three-point bending analyses revealed that the diamond pore design is more resistant to luminal collapse compared to the rectangular design. This data showed that by changing the scaffold pore design, a wide range of mechanical properties could be obtained. Furthermore, a full control over scaffold design and geometry can be achieved with the developed 4-axis extrusion-based system, which has not been reported with other techniques. This flexibility allow the manufacturing of scaffolds for diverse tubular tissue regeneration applications by designing suitable deposition patterns to match their mechanical pre-requisites.