| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Ding, Ming
University of Southern Denmark
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2020Strontium ion reinforced bioceramic scaffold for load bearing bone regenerationcitations
- 2018Calcium phosphate precipitation in experimental gaps between fluoride-containing fast-setting calcium silicate cement and dentincitations
- 2016Demineralized bone matrix and human cancellous bone enhance fixation of porous-coated titanium implants in sheepcitations
- 2015A reversal phase arrest uncoupling the bone formation and resorption contributes to the bone loss in glucocorticoid treated ovariectomised aged sheepcitations
- 2013Single-mode tunable laser emission in the single-exciton regime from colloidal nanocrystalscitations
- 2013Evaluating of bone healing around porous coated titanium implant and potential systematic bias on the traditional sampling methodcitations
- 2012Chalcogenide microsphere fabricated from fiber tapers using contact with a high-temperature ceramic surfacecitations
- 2012The effects of bone marrow aspirate, bone graft, and collagen composites on fixation of titanium implantscitations
- 2011Bioreactor activated graft material for early implant fixation in bone
- 2011A compact broadband microfiber Bragg gratingcitations
- 2010Demineralized bone matrix and human cancellous bone enhance fixation of titanium implants
- 2007The effect of bone marrow aspirate, bone graft and collagen composites on fixation of bone implants
Places of action
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article
Strontium ion reinforced bioceramic scaffold for load bearing bone regeneration
Abstract
Bone defects in load bearing areas require bone reconstruction with strong biomaterial having mechanical characteristics like cortical bone. Bioceramics are biomaterials that support bone formation as well as provide adequate mechanical properties. A strontium substitution of the bioceramic is expected to further increase its bioactivity by enhancing osteogenesis and protect the bone from osteoclastic resorption. The study involves development, characterization and in vivo testing of a newly developed strontium substituted hydroxyapatite based bioceramic scaffold (SrHAB) with sufficient biomechanical properties. Optimal concentration of strontium ion required for enhanced osteogenic differentiation was identified by comparing three compositions of SrHAB scaffold; namely Sr10HAB, Sr30HAB and Sr50 HAB for their Alkaline phosphatase activity in vitro. The selected Sr10HAB scaffold demonstrated in vivo bone formation with osteogenic differentiation of stromal derived mesenchymal stem cells (MSC) from human and ovine sources in ectopic and ovine models. Thus, Sr10HAB scaffold has a potential for application in load bearing bone requirements of orthopaedics and dentistry.