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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Oliveira, Ana L.
Universidade Católica Portuguesa
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2022Adenosine-loaded silk fibroin aerogel particles for wound healing
- 2022Opening new avenues for bioceramicscitations
- 2021New prospects in skin regeneration and repair using nanophased hydroxyapatite embedded in collagen nanofiberscitations
- 2021High efficient strategy for the production of hydroxyapatite/silk sericin nanocompositescitations
- 2020Hydroxyapatite/sericin compositescitations
- 2020High efficient strategy for the production of hydroxyapatite/silk sericin nanocomposites
- 2020Hydroxyapatite/sericin composites:a simple synthesis route under near-physiological conditions of temperature and pH and preliminary study of the effect of sericin on the biomineralization processcitations
- 2019Sterile and dual-porous aerogels scaffolds obtained through a multistep supercritical CO2-based approachcitations
- 2019Sterile and dual-porous aerogels scaffolds obtained through a multistep supercritical CO 2 -based approachcitations
- 2018Combinatory approach for developing silk fibroin scaffolds for cartilage regenerationcitations
- 2017Modulating cell adhesion to polybutylene succinate biotextile constructs for tissue engineering applicationscitations
- 2017Silk-based anisotropical 3D biotextiles for bone regenerationcitations
- 2017Core-shell silk hydrogels with spatially tuned conformations as drug-delivery systemcitations
- 2016Combinatory approach for developing silk fibroin-based scaffolds with hierarchical porosity and enhanced performance for cartilage tissue engineering applications
- 2013Evaluation of novel 3D architectures based on knitting technologies for engineering biological tissues
- 2012Aligned silk-based 3-D architectures for contact guidance in tissue engineeringcitations
- 2009Nucleation and growth of biomimetic apatite layers on 3D plotted biodegradable polymeric scaffoldscitations
- 2005Study of the influence of β-radiation on the properties and mineralization of different starch-based biomaterialscitations
- 2004Pre-mineralisation of starch/polycrapolactone bone tissue engineering scaffolds by a calcium-silicate-based processcitations
- 2003Biomimetic coating of starch based polymeric foams produced by a calcium silicate based methodologycitations
- 2003Bi-composite sandwich moldingscitations
- 2003Sodium silicate gel as a precursor for the in vitro nucleation and growth of a bone-like apatite coating in compact and porous polymeric structurescitations
- 2001Sodium silicate gel induced self-mineralization of different compact and porous polymeric structurescitations
Places of action
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article
Hydroxyapatite/sericin composites
Abstract
Synthesis of hydroxyapatite (HAp) and sericin (SS) nanocomposites was carried out by a simple precipitation method performed in batch in a stirred tank reactor (ST). The reaction was achieved by mixing a solution of calcium chloride dihydrate, in which SS was dissolved, with a solution of disodium hydrogen phosphate at 37 °C. Three experimental conditions were studied by varying the concentration of SS: HAp, HAp/SS1 (0.01 g/L of SS) and HAp/SS2 (1 g/L of SS). The chemical and physical properties of the resulting HAp/SS nanocomposites were studied using several techniques (Atomic Absorption Spectrometry, Ultraviolet-Visible Spectrophotometry, Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Selected area diffraction (SAED) and Thermogravimetric analysis (TGA)). pH profile was also monitored over time for each experimental condition. The results revealed that nano single-phased HAp was formed with both rod and plate-like shape. Additionally, the particles have low crystallinity, characteristic similar to biological HAp. Regarding the influence of SS, one observed that with increasing SS concentration there is an increase in the mean particle size and the number of plate-like particles, as well as an increase in the aggregation degree and a decrease of the crystallinity. Further, the composites obtained have an inorganic/organic composition comparable to bone. Finally, in vitro cytotoxicity showed that the synthetized nanoparticles are non-toxic and cell viability is higher for HAp and HAp/SS samples when compared to a commercially available HAp. The produced materials can thus be considered suitable candidates for bone related applications.