| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Zhou, Jie
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (31/31 displayed)
- 2024Biodegradation-affected fatigue behavior of extrusion-based additively manufactured porous iron–manganese scaffoldscitations
- 2023Biomechanical evaluation of additively manufactured patient-specific mandibular cage implants designed with a semi-automated workflowcitations
- 2023Extrusion-based 3D printing of biodegradable, osteogenic, paramagnetic, and porous FeMn-akermanite bone substitutescitations
- 2023Quality of AM implants in biomedical applicationcitations
- 2022Extrusion-based additive manufacturing of Mg-Zn alloy scaffoldscitations
- 2022Additive manufacturing of bioactive and biodegradable porous iron-akermanite composites for bone regenerationcitations
- 2022Poly(2-ethyl-2-oxazoline) coating of additively manufactured biodegradable porous ironcitations
- 2022Additive Manufacturing of Biomaterialscitations
- 2021Extrusion-based 3D printing of ex situ-alloyed highly biodegradable MRI-friendly porous iron-manganese scaffoldscitations
- 2021Additively Manufactured Biodegradable Porous Zinc Implants for Orthopeadic Applications
- 2021Extrusion-based 3D printed biodegradable porous ironcitations
- 2021Biocompatibility and Absorption Behavior in Vitro of Direct Printed Porous Iron Porous Implants
- 2021Lattice structures made by laser powder bed fusioncitations
- 2020Additively manufactured biodegradable porous zinccitations
- 2020Multi-material additive manufacturing technologies for Ti-, Mg-, and Fe-based biomaterials for bone substitutioncitations
- 2019Additively manufactured functionally graded biodegradable porous ironcitations
- 2019Modeling high temperature deformation characteristics of AA7020 aluminum alloy using substructure-based constitutive equations and mesh-free approximation methodcitations
- 2019Biodegradation-affected fatigue behavior of additively manufactured porous magnesiumcitations
- 2018Additively manufactured biodegradable porous ironcitations
- 2018A comprehensive investigation of the strengthening effects of dislocations, texture and low and high angle grain boundaries in ultrafine grained AA6063 aluminum alloycitations
- 2018Biodegradation and mechanical behavior of an advanced bioceramic-containing Mg matrix composite synthesized through in-situ solid-state oxidationcitations
- 2017Advanced bredigite-containing magnesium-matrix composites for biodegradable bone implant applicationscitations
- 2017Improvement of mechanical properties of AA6063 aluminum alloy after equal channel angular pressing by applying a two-stage solution treatmentcitations
- 2017Additively manufactured biodegradable porous magnesiumcitations
- 2017Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradationcitations
- 2016Simultaneous improvements of the strength and ductility of fine-grained AA6063 alloy with increasing number of ECAP passescitations
- 2016An investigation on the properties of injection-molded pure iron potentially for biodegradable stent applicationcitations
- 2015Analysis of the densification behaviour of titanium/carbamide powder mixtures in the preparation of biomedical titanium scaffolds.
- 2015In vitro degradation of magnesium metal matrix composites containing bredigite
- 2015Evolution of macro- and micro-pores in the porous structures of biomedical titanium scaffolds during isothermal sintering
- 2010Preliminary investigation on creep-fatigue regime in extrusion dies
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article
Advanced bredigite-containing magnesium-matrix composites for biodegradable bone implant applications
Abstract
<p>The present research was aimed at developing magnesium-matrix composites that could allow effective control over their physiochemical and mechanical responses when in contact with physiological solutions. A biodegradable, bioactive ceramic - bredigite was chosen as the reinforcing phase in the composites, based on the hypothesis that the silicon- and magnesium-containing ceramic could protect magnesium from fast corrosion and at the same time stimulate cell proliferation. Methods to prepare composites with integrated microstructures - a prerequisite to achieve controlled biodegradation were developed. A systematic experimental approach was taken in order to elucidate the in vitro biodegradation mechanisms and kinetics of the composites. It was found that the composites with 20–40% homogenously dispersed bredigite particles, prepared from powders, could indeed significantly decrease the degradation rate of magnesium by up to 24 times. Slow degradation of the composites resulted in the retention of the mechanical integrity of the composites within the strength range of cortical bone after 12 days of immersion in a cell culture medium. Cell attachment, cytotoxicity and bioactivity tests confirmed the stimulatory effects of bredigite embedded in the composites on the attachment, viability and differentiation of bone marrow stromal cells. Thus, the multiple benefits of adding bredigite to magnesium in enhancing degradation behavior, mechanical properties, biocompatibility and bioactivity were obtained. The results from this research showed the excellent potential of the bredigite-containing composites for bone implant applications, thus warranting further in vitro and in vivo research.</p>