| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Sopchenski Santos, Luciane
Vrije Universiteit Brussel
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (11/11 displayed)
- 2023Surface modification of biodegradable Mg alloy by adapting µEDM capabilities with cryogenically-treated tool electrodescitations
- 2021Improvement of wear and corrosion protection of PEO on AA2024 via sol-gel sealingcitations
- 2021Investigation of the long-term corrosion protection of sol-gel sealed PEO
- 2021Improvement of the corrosion performance of AA2024 by a duplex PEO/clay modified sol-gel nanocomposite coating
- 2020Crystallinity of TiO2 nanotubes and its effects on fibroblast viability, adhesion, and proliferationcitations
- 2020Barrier properties of Sol-Gel layer applied on PEO porous coatings for AA2024 corrosion protection
- 2020Annealing Temperature Effect on Tribocorrosion and Biocompatibility Properties of TiO2 Nanotubescitations
- 2018Characterization of the morphology, structure and wettability of phase dependent lamellar and nanotube oxides on anodized Ti-10Nb alloycitations
- 2018Bactericidal activity and cytotoxicity of a zinc doped PEO titanium coatingcitations
- 2017In-vitro cell adhesion and proliferation of adipose derived stem cell on hydroxyapatite composite surfacescitations
- 2015Electrochemical stability and bioactivity evaluation of Ti6Al4V surface coated with thin oxide by EIS for biomedical applicationscitations
Places of action
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article
In-vitro cell adhesion and proliferation of adipose derived stem cell on hydroxyapatite composite surfaces
Abstract
<p>The goal of this work was to enhance the mechanical strength and fracture toughness of brittle hydroxyapatite (HAP) by reinforcing it with nanocomposites such as graphene oxide (GO), carbon nanotubes (CNT) and Titania. The goal was also to evaluate the cytotoxicity and the cellular adhesion/proliferation of these composites. The composites were characterized for their crystallinity, functionality, morphology and mechanical properties. Altering the composition by adding 1 wt% GO and CNT significantly altered the wettability, hardness and roughness. Further, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FITR) and X-ray photoelectron spectroscopy (XPS) results confirm the crystal structure, bulk chemical composition and surface elemental composition respectively of the composites. The bulk hardness of HAP with CNT was significantly higher than that of HAP. The wettability of HAP with GO was significantly lower than that of HAP with GO and Titania. Adipose Derived Stem Cells (ADSCs) were used for this study to evaluate cytotoxicity and viability. HAP with CNT and HAP with CNT and Titania were found to be least cytotoxic compared to other composites as evaluated by Lactate Dehydrogenase (LDH) assay and alamarBlue assay. ADSC adhesion and proliferation was investigated after 1, 4 and 7 days of culture using fluorescence microscopy. All the composites nurtured ADSC adhesion and proliferation, however, distinct morphological changes were observed by using Scanning Electron Microscopy (SEM). Overall, these composites have the potential to be used as bone graft substitutes.</p>