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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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May, Pw
University of Bristol
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (9/9 displayed)
- 2022Experimental studies of electron affinity and work function from titanium on oxidised diamond (100) surfacescitations
- 2019Ab initio study of negative electron affinity from light metals on the oxygen-terminated diamond (1 1 1) surfacecitations
- 2017Bosonic Confinement and Coherence in Disordered Nanodiamond Arrayscitations
- 2016Fast electron transfer kinetics on novel interconnected nanospheres of graphene layers electrodescitations
- 2015Photochemically modified diamond-like carbon surfaces for neural interfacescitations
- 2015High surface area diamond-like carbon electrodes grown on vertically aligned carbon nanotubescitations
- 2013Metal-Bosonic Insulator-Superconductor Transition in Boron-Doped Granular Diamondcitations
- 2010Simulations of CVD diamond film growth using a simplified Monte Carlo model
- 2008Raman and conductivity studies of boron-doped microcrystalline diamond, facetted nanocrystalline diamond and cauliflower diamond filmscitations
Places of action
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article
Photochemically modified diamond-like carbon surfaces for neural interfaces
Abstract
Diamond-like carbon (DLC) was modified using a UV functionalization method to introduce surface-bound amine and aldehyde groups. The functionalization process rendered the DLC more hydrophilic and significantly increased the viability of neurons seeded to the surface. The amine functionalized DLC promoted adhesion of neurons and fostered neurite outgrowth to a degree indistinguishable from positive control substrates (glass coated with poly-L-lysine). The aldehyde-functionalized surfaces performed comparably to the amine functionalized surfaces and both additionally supported the adhesion and growth of primary rat Schwann cells. DLC has many properties that are desirable in biomaterials. With the UV functionalization method demonstrated here it may be possible to harness these properties for the development of implantable devices to interface with the nervous system.