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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Giugni, Andrea
University of Milan
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2024Thermal Treatment Effects on PMN-0.4PT/Fe Multiferroic Heterostructures
- 2017Experimental Route to Scanning Probe Hot Electron Nanoscopy (HENs) Applied to 2D Materialcitations
- 2017The role of surface tension in the crystallization of metal halide perovskitescitations
- 2016Laboratory injection molder for the fabrication of polymeric porous poly-epsilon-caprolactone scaffolds for preliminary mesenchymal stem cells tissue engineering applicationscitations
- 2015Fabrication, Mercury Intrusion Porosimetry Characterization and In Vitro Qualitative Analysis of Biocompatibility of Various Porosities Polycaprolactone Scaffoldscitations
- 2015Fabrication, Mercury Intrusion Porosimetry Characterization and In Vitro Qualitative Analysis of Biocompatibility of Various Porosities Polycaprolactone Scaffoldscitations
- 2015Development, characterization and cell cultural response of 3d biocompatible micro-patterned poly-ε-caprolactone scaffolds designed and fabricated integrating lithography and micromolding fabrication techniquescitations
- 2014Development, characterization and cell cultural response of 3d biocompatible micro-patterned poly-$ɛ$-caprolactone scaffolds designed and fabricated integrating lithography and micromolding fabrication techniquescitations
- 2014Adiabatic nanofocusing: Spectroscopy, transport and imaging investigation of the nano worldcitations
- 2013Molding of plasmonic resonances in metallic nanostructures: Dependence of the non-linear electric permittivity on system size and temperaturecitations
- 2012Ultraviolet and visible Brillouin scattering study of viscous relaxation in 3-methylpentane down to the glass transitioncitations
- 2012Nanoplasmonic structures for biophotonic applications: SERS overviewcitations
Places of action
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article
Laboratory injection molder for the fabrication of polymeric porous poly-epsilon-caprolactone scaffolds for preliminary mesenchymal stem cells tissue engineering applications
Abstract
This study presents a simple and rapid fabrication technique involving injection molding and particle leaching (IM/PL) to fabricate the porous scaffold for tissue engineering applications. Sodium chloride (NaCl) and Sucrose are separately mixed with the poly-epsilon-caprolactone (PCL) granules using a screwed thermo regulated extruder, than the biocompatible scaffolds are fabricated through injection molding. The micro/nano structure of the samples and their different grade of porosity were characterized by scanning electron microscopy and mercury intrusion porosimetry. Bone marrow-derived mesenchymal stem cells are chose to cell culture and Hoechst 33342 staining was used to verify the biocompatibility of the polymeric porous surfaces. We concluded that, by using the same fast solvent free injection/leaching process, the use of Sucrose as porogen, instead of NaCl, allowed the obtainment of biocompatible scaffolds with a higher grade of porosity with suitable cell adhesion capacity for tissue engineering purpose.