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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Nobbs, Angela
University of Bristol
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article
Bactericidal nanospike surfaces via thermal oxidation of Ti alloy substrates
Abstract
With the aim to fabricate bio-inspired antibacterial nanotopography surfaces, nanospikes with varying<br/>dimensions were grown on Ti alloy surfaces using a thermal oxidation method. By controlling the<br/>acetone vapour concentration inside the tube furnace, the resulting oxide surface changed from nanocolumn<br/>shapes to nanospikes with approximately 20 nm diameters. The nanospikee growth was demonstrated<br/>to work on 3D Ti alloy bead surfaces, which means translation of the method to implant<br/>surfaces would be possible. Microbiology studies using Escherichia coli. showed that the nanospikes on<br/>the Ti alloy surfaces has potential to reduce bacterial viability. More dead bacteria were present on the<br/>nanospike surfaces compared to a smooth control and a 40% reduction of viability was noted in bacterial<br/>suspensions incubated with a nanospike surface. It was shown that by annealing the Ti alloy surfaces<br/>prior to thermal oxidation, it is possible to grow vertically aligned nanospikes. This could be highly<br/>valuable when designing implant surfaces with antimicrobial properties