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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Banzhaf, Manuel
Newcastle University
in Cooperation with on an Cooperation-Score of 37%
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article
Design of novel Zn-Ag-Zr alloy with enhanced strength as a potential biodegradable implant material
Abstract
<p>In this study, a new biodegradable alloy from the Zn-Ag-Zr system was investigated. Most importantly, mechanical properties and ductility were significantly improved in designed Zn1Ag0.05Zr alloy in comparison to binary Zn1Ag and previously investigated Zn0.05Zr alloys (wt%). The characterized alloy reached values of yield strength, ultimate tensile strength and elongation to failure equal to 166 ± 2 MPa, 211 ± 1 MPa and 35 ± 1%, respectively. Simultaneous addition of both alloying elements contributed to solid solution strengthening, intermetallic Zr-rich phase formation, and effective grain refinement. Immersion and electrochemical in vitro corrosion tests showed a slight increase of degradation rate in ternary alloy up to 17.1 ± 1.0 μm/year and no significant loss of mechanical properties after 28-day of immersion in simulated physiological solution. In addition, the preliminary antimicrobial studies show antimicrobial activity of the investigated Zn-Ag-Zr alloy against Escherichia coli and Staphylococcus aureus. The presented results demonstrate that newly developed Zn-based alloy can be considered as a promising biodegradable material for medical applications.</p>