| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Kurczewska, Joanna
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (6/6 displayed)
- 2021The Electrospray (ESI) and Flowing Atmosphere-Pressure Afterglow (FAPA) Mass Spectrometry Studies of Nitrophenols (Plant Growth Stimulants) Removed Using Strong Base-Functionalized Materialscitations
- 2018Preparation of multifunctional cascade iron oxide nanoparticles for drug deliverycitations
- 2016Photoacoustic infrared spectroscopic studies of silica gels with organically functionalized surfacecitations
- 2010Copper removal by carbon nanomaterials bearing cyclam-functionalized silicacitations
- 2010Preparation and characterization of magnetic carbon nanomaterials bearing APTS-silica on their surfacecitations
- 2010Adsorption of metal ions on magnetic carbon nanomaterials bearing chitosan-functionalized silicacitations
Places of action
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article
Preparation of multifunctional cascade iron oxide nanoparticles for drug delivery
Abstract
A novel pH sensitive magnetic multifunctional nanomaterial was prepared for sustained release of drugs. Adamantane derivative (ADMA) was covalently attached to the iron (II, III) oxide nanoparticles. On the basis of host-guest interactions, a stable inclusion complex between adamantane and succinyl β-cyclodextrin (CD-COOH) with ionically bonded polyamidoamnie dendrimer was formed. The dendrimer was used as a drug carrier of ibuprofen (IBU) and methotrexate (MTX), model therapeutic agents. In pH 7.4 IBU and MTX were released from dendrimer in sustained manner with Korsmeyer-Peppas kinetic model and case I transport mechanism. In pH 1.2, only a little amount of IBU and MTX was released, while acidic environment contributed to the degradation of the inclusion complex (ADMA and CD-COOH) and thereby releasing of antiviral ADMA drug.</p>